Xpert MTB/RIF testing of stool samples for the diagnosis of pulmonary tuberculosis in children

Mark P. Nicol, Karalene Spiers, Lesley Workman, Washiefa Isaacs, Jacinta Munro, Faye Black, Widaad Zemanay, Heather J. Zar

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

In a pilot accuracy study, stool Xpert testing from 115 children with suspected pulmonary tuberculosis (PTB) detected 8/17 (47%) culture-confirmed tuberculosis cases, including 4/5 (80%) human immunodeficiency virus (HIV)-infected and 4/12 (33%) HIV-uninfected children. Sputum Xpert detected 11/17 (65%) cases. Stool holds promise for PTB diagnosis in HIV-infected children.

Original languageEnglish
Pages (from-to)E18-E21
JournalClinical Infectious Diseases
Volume57
Issue number3
DOIs
Publication statusPublished - 1 Aug 2013
Externally publishedYes

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