Xpert MTB/RIF for rapid diagnosis of tuberculous lymphadenitis from fine-needle-aspiration biopsy specimens

Louis J. Ligthelm, Mark P. Nicol, Kim G.P. Hoek, Rachael Jacobson, Paul D. Van Helden, Ben J. Marais, Robin M. Warren, Colleen A. Wright

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

This study demonstrates the excellent diagnostic accuracy of the Xpert MTB/RIF test in patients with tuberculous lymphadenitis. The test sensitivity and specificity were 96.7% (95% confidence interval [CI], 86.6 to 100%) and 88.9% (95% CI, 69.6 to 100%), respectively, and it correctly identified 6/6 (100%) of the cytology smear-negative/culture-positive cases and 1 of 2 (50%) rifampin-resistant cases.

Original languageEnglish
Pages (from-to)3967-3970
Number of pages4
JournalJournal of Clinical Microbiology
Volume49
Issue number11
DOIs
Publication statusPublished - 1 Nov 2011
Externally publishedYes

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