TY - JOUR
T1 - Wide-field TCSPC
T2 - Methods and applications
AU - Hirvonen, Liisa M.
AU - Suhling, Klaus
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Time-correlated single photon counting (TCSPC) is a widely used, robust and mature technique to measure the photon arrival time in applications such as fluorescence spectroscopy and microscopy, LIDAR and optical tomography. In the past few years there have been significant developments with wide-field TCSPC detectors, which can record the position as well as the arrival time of the photon simultaneously. In this review, we summarise different approaches used in wide-field TCSPC detection, and discuss their merits for different applications, with emphasis on fluorescence lifetime imaging.
AB - Time-correlated single photon counting (TCSPC) is a widely used, robust and mature technique to measure the photon arrival time in applications such as fluorescence spectroscopy and microscopy, LIDAR and optical tomography. In the past few years there have been significant developments with wide-field TCSPC detectors, which can record the position as well as the arrival time of the photon simultaneously. In this review, we summarise different approaches used in wide-field TCSPC detection, and discuss their merits for different applications, with emphasis on fluorescence lifetime imaging.
KW - fluorescence lifetime imaging
KW - microchannel plate
KW - single photon detection
KW - single-photon avalanche diode array
KW - time-correlated single photon counting
UR - http://www.scopus.com/inward/record.url?scp=85007109269&partnerID=8YFLogxK
U2 - 10.1088/1361-6501/28/1/012003
DO - 10.1088/1361-6501/28/1/012003
M3 - Review article
AN - SCOPUS:85007109269
VL - 28
JO - Measurement Science & Technology
JF - Measurement Science & Technology
SN - 0957-0233
IS - 1
M1 - 012003
ER -