TY - JOUR
T1 - What We Know About Neurocognitive Outcomes in Long-/Post-COVID-19 Adults
T2 - A Comprehensive Scoping Review
AU - Seibert, Susan
AU - Hanke, Alexander
AU - Wieberneit, Michelle
AU - Bieler, Luzie
AU - Gräfenkämper, Robin
AU - Klatt, Katrin
AU - Widmann, Catherine Nichols
PY - 2024/6
Y1 - 2024/6
N2 - This review assesses neurocognitive studies on long-/post-COVID-19 adult patients, highlighting the research gaps. We categorize populations by infection severity, demographics, inclusion of controls, and psychological/biological factors. Methodologically, we analyzed 73 studies (95,600 subjects) from December 2019 to October 2022 using PRISMA-ScR guidelines and the PICO framework. Our findings revealed that most studies lacked control groups (88 %) and reported unclear overall cognitive outcomes (73 %). While the studies frequently assessed executive functions (86 %) and attention (85 %), there were few longitudinal studies. Varied reporting on sample sizes further complicated the analysis. The identified gaps encompass convenience sampling, limited longitudinal studies, and inadequate use of cognitive test batteries, leading to a discrepancy between expected and reported outcomes. The absence of standardized comparisons and inconsistent statistical methods exacerbated these gaps.
AB - This review assesses neurocognitive studies on long-/post-COVID-19 adult patients, highlighting the research gaps. We categorize populations by infection severity, demographics, inclusion of controls, and psychological/biological factors. Methodologically, we analyzed 73 studies (95,600 subjects) from December 2019 to October 2022 using PRISMA-ScR guidelines and the PICO framework. Our findings revealed that most studies lacked control groups (88 %) and reported unclear overall cognitive outcomes (73 %). While the studies frequently assessed executive functions (86 %) and attention (85 %), there were few longitudinal studies. Varied reporting on sample sizes further complicated the analysis. The identified gaps encompass convenience sampling, limited longitudinal studies, and inadequate use of cognitive test batteries, leading to a discrepancy between expected and reported outcomes. The absence of standardized comparisons and inconsistent statistical methods exacerbated these gaps.
U2 - 10.1024/1016-264X/a000395
DO - 10.1024/1016-264X/a000395
M3 - Article
VL - 35
SP - 63
EP - 76
JO - Zeitschrift für Neuropsychologie
JF - Zeitschrift für Neuropsychologie
IS - 2
ER -