Ward reduction of gastroschisis in a single stage without general anaesthesia may increse the risk of short-term morbidities: Result of a prospective audit

Shripada Rao, S. Pirie, C. Minutillo, I. Gollow, Jan Dickinson, P. Jacoby

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    Ward reduction of gastroschisis in a single stage without the need for general inhalational anaesthesia (ward reduction) has been reported by some authors to be effective and safe. We introduced this practice to our neonatal unit 2 years ago.Aim: To compare the short-term outcomes of this new practice with the standard procedure of reduction under general anaesthesia (GA).Methods: Retrospective case series of all infants with gastroschisis between January 2004 and January 2008.Results: Twenty-seven infants were managed with the traditional approach and 11 infants underwent ward reduction without GA. Infants in the ward reduction group had an increased frequency for all the three major adverse events (ischemic necrosis of bowel: 27.3% vs. 3.7%, odds ratio (OR) 10.72, 95% confidence interval (CI): 0.72, 159.6; need for total parenteral nutrition (TPN) more than 60 days: 18% vs. 3.7%, OR 4.13, 95% CI: 0.28, 61.55; and unplanned return to theatre: 27.3% vs. 7.4%, OR 3.88, 95% CI: 0.44, 34.08), although none of these events reached statistical significance. There were no significant differences between the groups for the outcomes of time to reach full feeds, duration of hospital stay and number of days on antibiotics.Conclusions: These results raise concerns over the role of ward reduction of gastroschisis in a single sitting without the use of GA. Randomised trials with appropriate design and sample size are needed before embracing this method as a standard practice.
    Original languageEnglish
    Pages (from-to)384-388
    JournalJournal of Paediatrics and Child Health
    Issue number6
    Publication statusPublished - 2009


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