'Soft energy' provided within a thin film microfluidic platform, namely a vortex fluidic device (VFD), is effective in accelerating and promoting Diels-Alder reactions in the absence of any catalyst. Diels-Alder cycloadducts generated from different 9-substituted anthracenes and N-maleimides are formed in high yield in an aqueous medium using the confined mode of operation of the VFD. © 2014 Elsevier Ltd. All rights reserved.
Yasmin, L., Stubbs, K., & Raston, C. L. (2014). Vortex fluidic promoted Diels-Alder reactions in an aqueous medium. Tetrahedron Letters, 55(14), 2246-2248. https://doi.org/10.1016/j.tetlet.2014.02.077