We report on a UV-Visible HST imaging survey to mAB ~ 28 mag of the JWST North Ecliptic Pole (NEP) Time-Domain Field (TDF). Using near-CVZ opportunities, we observed 7 of 9 tiles with WFC3/UVIS in F275W and with ACS/WFC in F435W and F606W. Our HST survey will provide near-contiguous 3-filter coverage of the central r ≤ 5′ of this new community field for time-domain science with JWST (Jansen & Windhorst 2018). The JWST NEP TDF is located within JWST's northern Continuous Viewing Zone, will span ~14′ in diameter, is devoid of sources bright enough to saturate the NIRCam detectors, has low Galactic foreground extinction, and will be roughly circular in shape. JWST GTO program 1176 will initially sample the NEP TDF during Cycle 1 at four distinct orientations ("spokes") with JWST/NIRCam, and take NIRISS slitless grism spectroscopy in parallel such that it overlaps the coverage of an alternate NIRCam orientation. This is the only region in the sky where JWST can observe a clean extragalactic deep survey field of this size at arbitrary cadence or at arbitrary orientation. This will crucially enable a wide range of new and exciting time-domain science, including high-z transient searches and monitoring (e.g., SNe), variability studies from Active Galactic Nuclei to brown dwarf atmospheres, as well as proper motions of extreme scattered Kuiper Belt Objects and comets beyond the distance of Neptune, and of nearby brown dwarfs, low mass stars, and ultracool white dwarfs. Ancillary data across the electromagnetic spectrum will exist for this field when JWST science operations commence in 2021. This includes deep (mAB > 26 mag) wide-field (~23′×25′) Ugriz imaging of the JWST NEP TDF and surrounding area from LBT/LBC, Subaru/HSC, and GTC/HiPERCAM, YJHK to mAB ~ 24 mag from MMT/MMIRS, sub-μJy JVLA 3GHz and VLBA 5GHz radio observations, and deep (900ks) Chandra/ACIS X-ray images. Observations at long-wave radio (LOFAR) and (sub)mm (IRAM30m, JCMT, SMA) wavelengths, optical narrow-band spectrophotometry (J-PAS), and multi-object spectroscopy (MMT) are in progress, scheduled, or proposed, ensuring a rich legacy of the UV-Visible HST observations.