Utilising organs from hepatitis C virus PCR-positive donors in Western Australia

Peter Boan; Jagadish Jamboti; Michael Musk; Melanie Lavender; Jeremy P. Wrobel; Felicity Lee; Amit Shah; Lynette A. Pereira; J. Owen Robinson; Ashley Irish

doi:10.1111/imj.16345

Utilising organs from hepatitis C virus PCR-positive donors in Western Australia

Peter Boan, Jagadish Jamboti, Michael Musk, Melanie Lavender, Jeremy P. Wrobel, Felicity Lee, Amit Shah, Lynette A. Pereira, J. Owen Robinson, Ashley Irish

Internal Medicine

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We transplanted six solid organs from three hepatitis C virus (HCV) polymerase chain reaction (PCR)-positive donors during 2018–2023. Recipients were treated with glecaprevir/pibrentasvir or sofosbuvir/velpatasvir for 4–12 weeks, with all six achieving sustained virological response without significant adverse events. As occurs in other jurisdictions, solid organ transplants from HCR PCR-positive donors can be safely utilised in Australia.

Original language	English
Pages (from-to)	678-681
Number of pages	4
Journal	Internal Medicine Journal
Volume	54
Issue number	4
DOIs	https://doi.org/10.1111/imj.16345
Publication status	Published - Apr 2024

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10.1111/imj.16345

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title = "Utilising organs from hepatitis C virus PCR-positive donors in Western Australia",

abstract = "We transplanted six solid organs from three hepatitis C virus (HCV) polymerase chain reaction (PCR)-positive donors during 2018–2023. Recipients were treated with glecaprevir/pibrentasvir or sofosbuvir/velpatasvir for 4–12 weeks, with all six achieving sustained virological response without significant adverse events. As occurs in other jurisdictions, solid organ transplants from HCR PCR-positive donors can be safely utilised in Australia.",

keywords = "donor-derived infection, HCV, hepatitis C virus, transplantation",

author = "Peter Boan and Jagadish Jamboti and Michael Musk and Melanie Lavender and Wrobel, {Jeremy P.} and Felicity Lee and Amit Shah and Pereira, {Lynette A.} and Robinson, {J. Owen} and Ashley Irish",

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AU - Boan, Peter

AU - Jamboti, Jagadish

AU - Musk, Michael

AU - Lavender, Melanie

AU - Wrobel, Jeremy P.

AU - Lee, Felicity

AU - Shah, Amit

AU - Pereira, Lynette A.

AU - Robinson, J. Owen

AU - Irish, Ashley

PY - 2024/4

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N2 - We transplanted six solid organs from three hepatitis C virus (HCV) polymerase chain reaction (PCR)-positive donors during 2018–2023. Recipients were treated with glecaprevir/pibrentasvir or sofosbuvir/velpatasvir for 4–12 weeks, with all six achieving sustained virological response without significant adverse events. As occurs in other jurisdictions, solid organ transplants from HCR PCR-positive donors can be safely utilised in Australia.

AB - We transplanted six solid organs from three hepatitis C virus (HCV) polymerase chain reaction (PCR)-positive donors during 2018–2023. Recipients were treated with glecaprevir/pibrentasvir or sofosbuvir/velpatasvir for 4–12 weeks, with all six achieving sustained virological response without significant adverse events. As occurs in other jurisdictions, solid organ transplants from HCR PCR-positive donors can be safely utilised in Australia.

KW - donor-derived infection

KW - HCV

KW - hepatitis C virus

KW - transplantation

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JO - Internal Medicine Journal

JF - Internal Medicine Journal

IS - 4

ER -

Utilising organs from hepatitis C virus PCR-positive donors in Western Australia

Abstract

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