Utilisation of MMW Radiation to Facilitate Apoptosis in Triple Negative Breast Cancer Cell Lines via TRPV1 Receptor Sensitization

Anabel Sorolla, Sergii Romanenko, Peter H. Siegel, Vincent Wallace

Research output: Chapter in Book/Conference paperConference paper

Abstract

Triple-negative breast cancers (TNBC) are highly aggressive malignancies comprising 15-20 % of all breast cancers. TNBCs quickly acquire drug resistance mechanisms and are inherently resistant to radiotherapy, which significantly limits therapeutic options. Thus, there is a need to develop more selective and efficient therapeutic approaches to target this cancer subtype. In this study we investigate the applicability of MMW radiation as co-factor for prolonged sensitisation of TRPV1 receptor to promote the maximal channel activation with minimal tachyphylaxis to increase cancer cell death in TNBC.

Original languageEnglish
Title of host publication2019 - 44th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)
Place of PublicationUSA
PublisherIEEE, Institute of Electrical and Electronics Engineers
ISBN (Electronic)9781538682852
DOIs
Publication statusPublished - 2019
Event44th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2019 - Paris, France
Duration: 1 Sep 20196 Sep 2019

Publication series

NameInternational Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz
Volume2019-September
ISSN (Print)2162-2027
ISSN (Electronic)2162-2035

Conference

Conference44th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2019
CountryFrance
CityParis
Period1/09/196/09/19

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