Utilisation of MMW Radiation to Facilitate Apoptosis in Triple Negative Breast Cancer Cell Lines via TRPV1 Receptor Sensitization

Anabel Sorolla; Sergii Romanenko; Peter H. Siegel; Vincent Wallace

doi:10.1109/IRMMW-THz.2019.8873881

Utilisation of MMW Radiation to Facilitate Apoptosis in Triple Negative Breast Cancer Cell Lines via TRPV1 Receptor Sensitization

Anabel Sorolla, Sergii Romanenko, Peter H. Siegel, Vincent Wallace

Physics

Research output: Chapter in Book/Conference paper › Conference paper › peer-review

2 Citations (Scopus)

Abstract

Triple-negative breast cancers (TNBC) are highly aggressive malignancies comprising 15-20 % of all breast cancers. TNBCs quickly acquire drug resistance mechanisms and are inherently resistant to radiotherapy, which significantly limits therapeutic options. Thus, there is a need to develop more selective and efficient therapeutic approaches to target this cancer subtype. In this study we investigate the applicability of MMW radiation as co-factor for prolonged sensitisation of TRPV1 receptor to promote the maximal channel activation with minimal tachyphylaxis to increase cancer cell death in TNBC.

Original language	English
Title of host publication	2019 - 44th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)
Place of Publication	USA
Publisher	IEEE, Institute of Electrical and Electronics Engineers
ISBN (Electronic)	9781538682852
DOIs	https://doi.org/10.1109/IRMMW-THz.2019.8873881
Publication status	Published - 2019
Event	44th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2019 - Paris, France Duration: 1 Sept 2019 → 6 Sept 2019

Publication series

Name	International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz
Volume	2019-September
ISSN (Print)	2162-2027
ISSN (Electronic)	2162-2035

Conference

Conference	44th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2019
Country/Territory	France
City	Paris
Period	1/09/19 → 6/09/19

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1109/IRMMW-THz.2019.8873881

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Sorolla, A., Romanenko, S., Siegel, P. H., & Wallace, V. (2019). Utilisation of MMW Radiation to Facilitate Apoptosis in Triple Negative Breast Cancer Cell Lines via TRPV1 Receptor Sensitization. In 2019 - 44th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz) Article 8873881 (International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz; Vol. 2019-September). IEEE, Institute of Electrical and Electronics Engineers. https://doi.org/10.1109/IRMMW-THz.2019.8873881

Sorolla, Anabel ; Romanenko, Sergii ; Siegel, Peter H. et al. / Utilisation of MMW Radiation to Facilitate Apoptosis in Triple Negative Breast Cancer Cell Lines via TRPV1 Receptor Sensitization. 2019 - 44th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz). USA : IEEE, Institute of Electrical and Electronics Engineers, 2019. (International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz).

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title = "Utilisation of MMW Radiation to Facilitate Apoptosis in Triple Negative Breast Cancer Cell Lines via TRPV1 Receptor Sensitization",

abstract = "Triple-negative breast cancers (TNBC) are highly aggressive malignancies comprising 15-20 % of all breast cancers. TNBCs quickly acquire drug resistance mechanisms and are inherently resistant to radiotherapy, which significantly limits therapeutic options. Thus, there is a need to develop more selective and efficient therapeutic approaches to target this cancer subtype. In this study we investigate the applicability of MMW radiation as co-factor for prolonged sensitisation of TRPV1 receptor to promote the maximal channel activation with minimal tachyphylaxis to increase cancer cell death in TNBC.",

author = "Anabel Sorolla and Sergii Romanenko and Siegel, {Peter H.} and Vincent Wallace",

year = "2019",

doi = "10.1109/IRMMW-THz.2019.8873881",

language = "English",

series = "International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz",

publisher = "IEEE, Institute of Electrical and Electronics Engineers",

booktitle = "2019 - 44th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)",

address = "United States",

note = "44th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2019 ; Conference date: 01-09-2019 Through 06-09-2019",

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Sorolla, A, Romanenko, S, Siegel, PH & Wallace, V 2019, Utilisation of MMW Radiation to Facilitate Apoptosis in Triple Negative Breast Cancer Cell Lines via TRPV1 Receptor Sensitization. in 2019 - 44th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)., 8873881, International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz, vol. 2019-September, IEEE, Institute of Electrical and Electronics Engineers, USA, 44th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2019, Paris, France, 1/09/19. https://doi.org/10.1109/IRMMW-THz.2019.8873881

Utilisation of MMW Radiation to Facilitate Apoptosis in Triple Negative Breast Cancer Cell Lines via TRPV1 Receptor Sensitization. / Sorolla, Anabel; Romanenko, Sergii; Siegel, Peter H. et al.
2019 - 44th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz). USA: IEEE, Institute of Electrical and Electronics Engineers, 2019. 8873881 (International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz; Vol. 2019-September).

Research output: Chapter in Book/Conference paper › Conference paper › peer-review

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T1 - Utilisation of MMW Radiation to Facilitate Apoptosis in Triple Negative Breast Cancer Cell Lines via TRPV1 Receptor Sensitization

AU - Sorolla, Anabel

AU - Romanenko, Sergii

AU - Siegel, Peter H.

AU - Wallace, Vincent

PY - 2019

Y1 - 2019

N2 - Triple-negative breast cancers (TNBC) are highly aggressive malignancies comprising 15-20 % of all breast cancers. TNBCs quickly acquire drug resistance mechanisms and are inherently resistant to radiotherapy, which significantly limits therapeutic options. Thus, there is a need to develop more selective and efficient therapeutic approaches to target this cancer subtype. In this study we investigate the applicability of MMW radiation as co-factor for prolonged sensitisation of TRPV1 receptor to promote the maximal channel activation with minimal tachyphylaxis to increase cancer cell death in TNBC.

AB - Triple-negative breast cancers (TNBC) are highly aggressive malignancies comprising 15-20 % of all breast cancers. TNBCs quickly acquire drug resistance mechanisms and are inherently resistant to radiotherapy, which significantly limits therapeutic options. Thus, there is a need to develop more selective and efficient therapeutic approaches to target this cancer subtype. In this study we investigate the applicability of MMW radiation as co-factor for prolonged sensitisation of TRPV1 receptor to promote the maximal channel activation with minimal tachyphylaxis to increase cancer cell death in TNBC.

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U2 - 10.1109/IRMMW-THz.2019.8873881

DO - 10.1109/IRMMW-THz.2019.8873881

M3 - Conference paper

AN - SCOPUS:85074733684

T3 - International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz

BT - 2019 - 44th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)

PB - IEEE, Institute of Electrical and Electronics Engineers

CY - USA

T2 - 44th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2019

Y2 - 1 September 2019 through 6 September 2019

ER -

Sorolla A, Romanenko S, Siegel PH, Wallace V. Utilisation of MMW Radiation to Facilitate Apoptosis in Triple Negative Breast Cancer Cell Lines via TRPV1 Receptor Sensitization. In 2019 - 44th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz). USA: IEEE, Institute of Electrical and Electronics Engineers. 2019. 8873881. (International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz). doi: 10.1109/IRMMW-THz.2019.8873881

Utilisation of MMW Radiation to Facilitate Apoptosis in Triple Negative Breast Cancer Cell Lines via TRPV1 Receptor Sensitization

Abstract

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