Using the 7-point checklist as a diagnostic aid for pigmented skin lesions in general practice: A diagnostic validation study

F.M. Walter, A.T. Prevost, J. Vasconcelos, Philip Hall, N.P. Burrows, H.C. Morris, A.L.K. Kinmonth, J.D. Emery

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    29 Citations (Scopus)

    Abstract

    Background GPs need to recognise significant pigmented skin lesions, given rising UK incidence rates for malignant melanoma. The 7-point checklist (7PCL) has been recommended by NICE (2005) for routine use in UK general practice to identify clinically significant lesions which require urgent referral. Aim To validate the Original and Weighted versions of the 7PCL in the primary care setting. Design and setting Diagnostic validation study, using data from a SIAscopic diagnostic aid randomised controlled trial in eastern England. Method Adults presenting in general practice with a pigmented skin lesion that could not be immediately diagnosed as benign were recruited into the trial. Reference standard diagnoses were histology or dermatology expert opinion; 7PCL scores were calculated blinded to the reference diagnosis. A case was defined as a clinically significant lesion for primary care referral to secondary care (total 1436 lesions: 225 cases, 1211 controls); or melanoma (36). Results For diagnosing clinically significant lesions there was a difference between the performance of the Original and Weighted 7PCLs (respectively, area under curve: 0.66, 0.69, difference = 0.03, P
    Original languageEnglish
    Pages (from-to)e345-e353
    JournalBritish Journal of General Practice
    Volume63
    Issue number610
    DOIs
    Publication statusPublished - 2013

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