Using systems genetics to understanding the etiology of complex disease

Ramesh Ram, Grant Morahan

Research output: Chapter in Book/Conference paperChapter

2 Citations (Scopus)

Abstract

Here, we discuss Systems Genetics applications for systematic evaluation of candidate causal genes together with follow-up bioinformatics pathway analysis. The aim of this chapter is to illustrate analytic procedures and we provide examples in the context of Type 1 diabetes (T1day), the risk of which is conferred by over 60 loci. We also describe the Type 1 Diabetes Systems Genetics website and provide a guide for its use and application to other diseases.

Original languageEnglish
Title of host publicationSystems Genetics
Subtitle of host publicationMethods and Protocols
EditorsKlaus Schughart, Robert W. Williams
PublisherHumana Press
Pages597-606
Number of pages10
Volume1488
ISBN (Electronic)9781493964277
ISBN (Print)9781493964253
DOIs
Publication statusPublished - 2016

Publication series

NameMethods in Molecular Biology
Volume1488
ISSN (Print)10643745

Fingerprint Dive into the research topics of 'Using systems genetics to understanding the etiology of complex disease'. Together they form a unique fingerprint.

Cite this