Updated imaging findings in congenital Zika Syndrome: A disease story that is still being written

Maria de Fatima Viana Vasco Aragao, Natacha Calheiros de Lima Petribu, Vanessa van der Linden, Marcelo Moraes Valenca, Carlos Alexandre Antunes de Brito, Paul M. Parizel

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

In congenital Zika virus syndrome (CZS), the most frequent radiological findings are calcifications in the cortical-white matter junction and malformations of cortical development (pachygyria or polymicrogyria, which occur predominantly in the frontal lobes, or a simplified gyral pattern), ventriculomegaly, enlargement of the cisterna magna and the extra-axial subarachnoid space, corpus callosum abnormalities, and reduced brain volume. This syndrome can also result in a decrease in the brainstem and cerebellum volumes and delayed myelination. Infants with CZS may show venous thrombosis and lenticulostriate vasculopathies. Over a 3-year follow-up period, many infants with CZS showed hydrocephalus, reduction in brain calcifications, and greater reduction in brain thickness.

Original languageEnglish
Pages (from-to)1-14
Number of pages14
JournalTopics in magnetic resonance imaging : TMRI
Volume28
Issue number1
DOIs
Publication statusPublished - 1 Feb 2019

Fingerprint Dive into the research topics of 'Updated imaging findings in congenital Zika Syndrome: A disease story that is still being written'. Together they form a unique fingerprint.

  • Cite this

    de Fatima Viana Vasco Aragao, M., de Lima Petribu, N. C., van der Linden, V., Valenca, M. M., de Brito, C. A. A., & Parizel, P. M. (2019). Updated imaging findings in congenital Zika Syndrome: A disease story that is still being written. Topics in magnetic resonance imaging : TMRI, 28(1), 1-14. https://doi.org/10.1097/RMR.0000000000000193