This thesis uses images derived from remote sensors, and household surveys to investigate physiographic, socio-economic and policy drivers of land use and land cover change, and factors affecting forest-based livelihoods, in the Chure region of Nepal. The results indicate deforestation from 1988 to 2001, and an increase of forest cover from 2001 to 2014. Protected Areas were effective in preventing deforestation, while Collaborative Forest Management was not significant in preventing forest loss. Factors associated with deforestation were increased population, landscape fragility and overgrazing. Poorer households with larger families and more livestock were found to be more forest-dependent.