UDP-glucuronosyltransferase-dependent bioactivation of clofibric acid to a DNA-damaging intermediate in mouse hepatocytes

Pharmacology, Toxicology and Pharmaceutical Science

• Glucuronide 100%
• Clofibric Acid 100%
• DNA 83%
• Cell Nucleus DNA 33%
• Pathogenesis 16%
• Glucuronosyltransferase 16%
• Bioactivation 16%
• Borneol 16%
• Comet Assay 16%
• Aglycone 16%
• Gel Electrophoresis 16%
• Cell Protein 16%
• Plasmid DNA 16%

Agricultural and Biological Sciences

• DNA 100%
• Clofibric Acid 100%
• Hepatocyte 50%
• Hepatocyte 50%
• DNA Damage 33%
• Proteins 16%
• Transfection 16%
• Gel Electrophoresis 16%
• Comet Assay 16%
• Reticulum 16%

Engineering

• Hepatocytes 100%
• Glucuronidation 100%
• Baseline Level 33%
• Reticulum 33%
• Single Cell 33%
• Nuclear Attack 33%
• Cell Protein 33%
• Gel Electrophoresis 33%