Two novel genetic variants in the mineralocorticoid receptor gene associated with spontaneous preterm birth

I. Christiaens; Wei Ang; L.N. Gordon; X. Fang; S.M. Williams; Craig Pennell; D.M. Olson

doi:10.1186/s12881-015-0205-y

Two novel genetic variants in the mineralocorticoid receptor gene associated with spontaneous preterm birth

I. Christiaens, Wei Ang, L.N. Gordon, X. Fang, S.M. Williams, Craig Pennell, D.M. Olson

Graduate Research School

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

© 2015 Christiaens et al. Background: Preterm birth is the leading cause of mortality and morbidity in newborn infants. Its etiology is multifactorial with genes and environmental factors, including chronic maternal stress, contributing to its risk. Our objective was to investigate whether single nucleotide polymorphisms (SNPs) in genes involved in the stress response are associated with spontaneous preterm birth using a candidate gene approach. Methods: A total of 210 cases (singleton spontaneous preterm birth at

Original language	English
Pages (from-to)	1-8
Journal	BMC Medical Genetics
Volume	16
Issue number	1
DOIs	https://doi.org/10.1186/s12881-015-0205-y
Publication status	Published - 2015

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AU - Ang, Wei

AU - Gordon, L.N.

AU - Fang, X.

AU - Williams, S.M.

AU - Pennell, Craig

AU - Olson, D.M.

PY - 2015

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AB - © 2015 Christiaens et al. Background: Preterm birth is the leading cause of mortality and morbidity in newborn infants. Its etiology is multifactorial with genes and environmental factors, including chronic maternal stress, contributing to its risk. Our objective was to investigate whether single nucleotide polymorphisms (SNPs) in genes involved in the stress response are associated with spontaneous preterm birth using a candidate gene approach. Methods: A total of 210 cases (singleton spontaneous preterm birth at

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JF - BMC Medical Genetics

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Two novel genetic variants in the mineralocorticoid receptor gene associated with spontaneous preterm birth

Abstract

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