Two-dimensional optimization of a stent for an aneurysm

K. Srinivas; S. Townsend; C. J. Lee; T. Nakayama; M. Ohta; S. Obayashi; T. Yamaguchi

doi:10.1115/1.4001861

Two-dimensional optimization of a stent for an aneurysm

K. Srinivas, S. Townsend, C. J. Lee, T. Nakayama, M. Ohta, S. Obayashi, T. Yamaguchi

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

This work attempts to optimize stents that are implanted at the neck of coronary or cerebral aneurysms to effect a flow diversion. A two-dimensional version of the stent, which is a series of struts and gaps placed at the neck, is considered as the first step. Optimization is carried out based on the principles of exploration of design space using reductions in velocity and vorticity in the aneurysm dome as the objective functions. Latin hypercube sampling first develops 30-60 samples of a strut-gap arrangement. Flow past an aneurysm with each of these samples is computed using the commercial software FLUENT and the objective functions evaluated. This is followed by a Kriging procedure that identifies the nondominated solutions to the system, which are the optimized candidates. Three different cases of stents with rectangular or circular struts are considered. It is found that placing struts in the proximal region of the neck gives the best flow diversion.

Original language	English
Article number	021003
Journal	Journal of Medical Devices, Transactions of the ASME
Volume	4
Issue number	2
DOIs	https://doi.org/10.1115/1.4001861
Publication status	Published - 1 Jun 2010
Externally published	Yes

Access to Document

10.1115/1.4001861

Cite this

@article{8343045d5a5b4fb8b53fdc9ff1d68dd2,

title = "Two-dimensional optimization of a stent for an aneurysm",

abstract = "This work attempts to optimize stents that are implanted at the neck of coronary or cerebral aneurysms to effect a flow diversion. A two-dimensional version of the stent, which is a series of struts and gaps placed at the neck, is considered as the first step. Optimization is carried out based on the principles of exploration of design space using reductions in velocity and vorticity in the aneurysm dome as the objective functions. Latin hypercube sampling first develops 30-60 samples of a strut-gap arrangement. Flow past an aneurysm with each of these samples is computed using the commercial software FLUENT and the objective functions evaluated. This is followed by a Kriging procedure that identifies the nondominated solutions to the system, which are the optimized candidates. Three different cases of stents with rectangular or circular struts are considered. It is found that placing struts in the proximal region of the neck gives the best flow diversion.",

keywords = "Aneurysm, Flow diversion, Optimization, Stents, Strut position",

author = "K. Srinivas and S. Townsend and Lee, {C. J.} and T. Nakayama and M. Ohta and S. Obayashi and T. Yamaguchi",

year = "2010",

month = jun,

day = "1",

doi = "10.1115/1.4001861",

language = "English",

volume = "4",

journal = "Journal of Medical Devices",

issn = "1932-6181",

publisher = "ASME International",

number = "2",

}

TY - JOUR

T1 - Two-dimensional optimization of a stent for an aneurysm

AU - Srinivas, K.

AU - Townsend, S.

AU - Lee, C. J.

AU - Nakayama, T.

AU - Ohta, M.

AU - Obayashi, S.

AU - Yamaguchi, T.

PY - 2010/6/1

Y1 - 2010/6/1

N2 - This work attempts to optimize stents that are implanted at the neck of coronary or cerebral aneurysms to effect a flow diversion. A two-dimensional version of the stent, which is a series of struts and gaps placed at the neck, is considered as the first step. Optimization is carried out based on the principles of exploration of design space using reductions in velocity and vorticity in the aneurysm dome as the objective functions. Latin hypercube sampling first develops 30-60 samples of a strut-gap arrangement. Flow past an aneurysm with each of these samples is computed using the commercial software FLUENT and the objective functions evaluated. This is followed by a Kriging procedure that identifies the nondominated solutions to the system, which are the optimized candidates. Three different cases of stents with rectangular or circular struts are considered. It is found that placing struts in the proximal region of the neck gives the best flow diversion.

AB - This work attempts to optimize stents that are implanted at the neck of coronary or cerebral aneurysms to effect a flow diversion. A two-dimensional version of the stent, which is a series of struts and gaps placed at the neck, is considered as the first step. Optimization is carried out based on the principles of exploration of design space using reductions in velocity and vorticity in the aneurysm dome as the objective functions. Latin hypercube sampling first develops 30-60 samples of a strut-gap arrangement. Flow past an aneurysm with each of these samples is computed using the commercial software FLUENT and the objective functions evaluated. This is followed by a Kriging procedure that identifies the nondominated solutions to the system, which are the optimized candidates. Three different cases of stents with rectangular or circular struts are considered. It is found that placing struts in the proximal region of the neck gives the best flow diversion.

KW - Aneurysm

KW - Flow diversion

KW - Optimization

KW - Stents

KW - Strut position

UR - http://www.scopus.com/inward/record.url?scp=77956301329&partnerID=8YFLogxK

U2 - 10.1115/1.4001861

DO - 10.1115/1.4001861

M3 - Article

AN - SCOPUS:77956301329

VL - 4

JO - Journal of Medical Devices

JF - Journal of Medical Devices

SN - 1932-6181

IS - 2

M1 - 021003

ER -

Two-dimensional optimization of a stent for an aneurysm

Abstract

Access to Document

Other files and links

Fingerprint

Cite this