Turning the Tap: Conformational Control of Quantum Interference to Modulate Single-Molecule Conductance

Feng Jiang, Douglas I. Trupp, Norah Algethami, Haining Zheng, Wenxiang He, Afaf Alqorashi, Chenxu Zhu, Chun Tang, Ruihao Li, Junyang Liu, Hatef Sadeghi, Jia Shi, Ross Davidson, Marcus Korb, Alexandre N. Sobolev, Masnun Naher, Sara Sangtarash, Paul J. Low, Wenjing Hong, Colin J. Lambert

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)


Together with the more intuitive and commonly recognized conductance mechanisms of charge-hopping and tunneling, quantum-interference (QI) phenomena have been identified as important factors affecting charge transport through molecules. Consequently, establishing simple and flexible molecular-design strategies to understand, control, and exploit QI in molecular junctions poses an exciting challenge. Here we demonstrate that destructive quantum interference (DQI) in meta-substituted phenylene ethylene-type oligomers (m-OPE) can be tuned by changing the position and conformation of methoxy (OMe) substituents at the central phenylene ring. These substituents play the role of molecular-scale taps, which can be switched on or off to control the current flow through a molecule. Our experimental results conclusively verify recently postulated magic-ratio and orbital-product rules, and highlight a novel chemical design strategy for tuning and gating DQI features to create single-molecule devices with desirable electronic functions.

Original languageEnglish
Pages (from-to)18987-18993
Number of pages7
JournalAngewandte Chemie - International Edition
Issue number52
Early online date15 Oct 2019
Publication statusPublished - 19 Dec 2019


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