Abstract
Head and neck cancer (HNC) is a common cancer, with high patient morbidity and mortality. Standard methods of diagnosis and disease monitoring remain limited to invasive tumoural biopsy and serial imaging. My PhD project plans to perform comprehensive assessments of tumor-derived extracellular vesicles (EVs) and their potential as a novel biomarker in HNC patients on treatment. I will systematically and comprehensively analyse tumor-derived EVs levels, sizes, concentrations, and content of associated DNA, RNA, and characterise immune profiles to explore the utility of EV as a non-invasive source of tumour material for molecular assessment in serum from patients on therapy.
| Original language | English |
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| Qualification | Doctor of Philosophy |
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| Award date | 13 Oct 2023 |
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| Publication status | Unpublished - 2023 |
Access to Document
- THESIS - DOCTOR OF PHILOSOPHY - NGUYEN Bella Hai Van - 2023_
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