Triblock polymeric micelles as an emerging nanocarrier for drug delivery

This chapter focuses mainly on the ability of novel triblock polymeric micelles as delivery systems for different drugs. Poor water solubility is one of the primary factors that limit dissolution and results in a low dissolution rates and insufficient intestinal penetration, which leads to the limited therapeutic efficacy of numerous available drugs. Self-assembly of amphiphilic polymers results in the production of polymeric micelles. These are distinctive nanocarriers that have unique features; they show no to minimal toxicity, increase blood circulation time, have relatively high biological compatibility, and increase dissolution rates and delivery of hydrophilic drugs. Most studies involving specific drug targeting and distribution have been designed to reduce drug degradation and improve overall bioavailability. This chapter describes how we can create several forms of triblock polymeric micelles that can be employed for selective transport of drugs meant for specific pathological tissues or organs of the body. Studies done on different pathway for the delivery of drugs using polymeric micelles are also covered, along with their applications for anticancer drug therapy and treatment of other diseases.