Les ARN de transfert une nouvelle source de petits ARN non-codants chez Arabidopsis thaliana

Translated title of the contribution: Transfer RNAs are a new source of small non-coding RNAs in Arabidopsis thaliana

Geoffrey Eugene Andre Morelle

Research output: ThesisDoctoral Thesis

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Abstract

Recently a class of small RNAs (tRNA derived RNA fragments :tRFs) has emerged. In plants, despite that the existence of RFs has been reported, only few data are available. Three questions have been addressed. What enzyme is responsible or tRF biogenesis, where are tRFs generated and are tRFs only degradation by-products? Using various experiments we confirmed the existence of tAFs in plants, we also identified endonucleases that were good candidates for tRNA cleavage. Further experiments ted us to abetter understanding of tRFs function and biogenesis.
Original languageFrench
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Award date23 Jan 2017
Publication statusUnpublished - 2015

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