Trajectories of Irregular Word Reading ability as a Proxy for Premorbid Intelligence in Alzheimer’s Disease, Mild Cognitive Impairment, and Healthy Aging: A Longitudinal Study

Michael George Weinborn, Romola Starr Bucks, Hamid Sohrabi, Stephanie Ruth Rainey Smith, Belinda M. Brown, Samantha Gardener, A. Gozt, D Christensen, G. Savage, S. Laws, K Taddei, P Maruff, J. Robertson, K. Ellis, D. Ames, C Masters, C Rowe, R Martins

Research output: Contribution to journalArticle

30 Downloads (Pure)

Abstract

he ability to read irregularly spelled words is commonly used to estimate premorbid intelligence, as this ability has been thought to be resistant to early effects of neurodegenerative disorders. However, studies evaluating decline of this skill in Alzheimer�s disease (AD) have produced conflicting results. Irregular word reading was assessed three times over 36 months in a large (N = 995) sample, including healthy control, AD, and Mild Cognitive Impairment (MCI) groups. At baseline, MCI and AD groups read correctly an average of 3.01 and 7.39 fewer words, respectively, than healthy controls. The MCI group�s performance remained stable during the study, but the AD group declined. Importantly, the observed decline was likely an underestimate, as significant numbers of the AD participants (42.6%) could not complete the task at follow-up. Use of alternate (e.g., demographics-based) methods is advised to augment or replace word pronunciation in estimating premorbid intelligence in individuals with even mild AD. © 2018 American Psychological Association.
Original languageEnglish
Number of pages9
JournalPsychological Assessment
DOIs
Publication statusE-pub ahead of print - 21 May 2018

Fingerprint

Aptitude
Proxy
Intelligence
Longitudinal Studies
Reading
Alzheimer Disease
Neurodegenerative Diseases
Cognitive Dysfunction
Demography

Cite this

Weinborn, Michael George ; Bucks, Romola Starr ; Sohrabi, Hamid ; Rainey Smith, Stephanie Ruth ; Brown, Belinda M. ; Gardener, Samantha ; Gozt, A. ; Christensen, D ; Savage, G. ; Laws, S. ; Taddei, K ; Maruff, P ; Robertson, J. ; Ellis, K. ; Ames, D. ; Masters, C ; Rowe, C ; Martins, R. / Trajectories of Irregular Word Reading ability as a Proxy for Premorbid Intelligence in Alzheimer’s Disease, Mild Cognitive Impairment, and Healthy Aging : A Longitudinal Study. In: Psychological Assessment. 2018.
@article{fd7268be392049f39282b34790cda91e,
title = "Trajectories of Irregular Word Reading ability as a Proxy for Premorbid Intelligence in Alzheimer’s Disease, Mild Cognitive Impairment, and Healthy Aging: A Longitudinal Study",
abstract = "he ability to read irregularly spelled words is commonly used to estimate premorbid intelligence, as this ability has been thought to be resistant to early effects of neurodegenerative disorders. However, studies evaluating decline of this skill in Alzheimer�s disease (AD) have produced conflicting results. Irregular word reading was assessed three times over 36 months in a large (N = 995) sample, including healthy control, AD, and Mild Cognitive Impairment (MCI) groups. At baseline, MCI and AD groups read correctly an average of 3.01 and 7.39 fewer words, respectively, than healthy controls. The MCI group�s performance remained stable during the study, but the AD group declined. Importantly, the observed decline was likely an underestimate, as significant numbers of the AD participants (42.6{\%}) could not complete the task at follow-up. Use of alternate (e.g., demographics-based) methods is advised to augment or replace word pronunciation in estimating premorbid intelligence in individuals with even mild AD. {\circledC} 2018 American Psychological Association.",
author = "Weinborn, {Michael George} and Bucks, {Romola Starr} and Hamid Sohrabi and {Rainey Smith}, {Stephanie Ruth} and Brown, {Belinda M.} and Samantha Gardener and A. Gozt and D Christensen and G. Savage and S. Laws and K Taddei and P Maruff and J. Robertson and K. Ellis and D. Ames and C Masters and C Rowe and R Martins",
year = "2018",
month = "5",
day = "21",
doi = "10.1037/pas0000565",
language = "English",
journal = "Psychological Assessment",
issn = "1040-3590",
publisher = "American Psychological Association",

}

Weinborn, MG, Bucks, RS, Sohrabi, H, Rainey Smith, SR, Brown, BM, Gardener, S, Gozt, A, Christensen, D, Savage, G, Laws, S, Taddei, K, Maruff, P, Robertson, J, Ellis, K, Ames, D, Masters, C, Rowe, C & Martins, R 2018, 'Trajectories of Irregular Word Reading ability as a Proxy for Premorbid Intelligence in Alzheimer’s Disease, Mild Cognitive Impairment, and Healthy Aging: A Longitudinal Study' Psychological Assessment. https://doi.org/10.1037/pas0000565

Trajectories of Irregular Word Reading ability as a Proxy for Premorbid Intelligence in Alzheimer’s Disease, Mild Cognitive Impairment, and Healthy Aging : A Longitudinal Study. / Weinborn, Michael George; Bucks, Romola Starr; Sohrabi, Hamid; Rainey Smith, Stephanie Ruth; Brown, Belinda M.; Gardener, Samantha; Gozt, A.; Christensen, D; Savage, G.; Laws, S.; Taddei, K; Maruff, P; Robertson, J.; Ellis, K.; Ames, D.; Masters, C; Rowe, C; Martins, R.

In: Psychological Assessment, 21.05.2018.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Trajectories of Irregular Word Reading ability as a Proxy for Premorbid Intelligence in Alzheimer’s Disease, Mild Cognitive Impairment, and Healthy Aging

T2 - A Longitudinal Study

AU - Weinborn, Michael George

AU - Bucks, Romola Starr

AU - Sohrabi, Hamid

AU - Rainey Smith, Stephanie Ruth

AU - Brown, Belinda M.

AU - Gardener, Samantha

AU - Gozt, A.

AU - Christensen, D

AU - Savage, G.

AU - Laws, S.

AU - Taddei, K

AU - Maruff, P

AU - Robertson, J.

AU - Ellis, K.

AU - Ames, D.

AU - Masters, C

AU - Rowe, C

AU - Martins, R

PY - 2018/5/21

Y1 - 2018/5/21

N2 - he ability to read irregularly spelled words is commonly used to estimate premorbid intelligence, as this ability has been thought to be resistant to early effects of neurodegenerative disorders. However, studies evaluating decline of this skill in Alzheimer�s disease (AD) have produced conflicting results. Irregular word reading was assessed three times over 36 months in a large (N = 995) sample, including healthy control, AD, and Mild Cognitive Impairment (MCI) groups. At baseline, MCI and AD groups read correctly an average of 3.01 and 7.39 fewer words, respectively, than healthy controls. The MCI group�s performance remained stable during the study, but the AD group declined. Importantly, the observed decline was likely an underestimate, as significant numbers of the AD participants (42.6%) could not complete the task at follow-up. Use of alternate (e.g., demographics-based) methods is advised to augment or replace word pronunciation in estimating premorbid intelligence in individuals with even mild AD. © 2018 American Psychological Association.

AB - he ability to read irregularly spelled words is commonly used to estimate premorbid intelligence, as this ability has been thought to be resistant to early effects of neurodegenerative disorders. However, studies evaluating decline of this skill in Alzheimer�s disease (AD) have produced conflicting results. Irregular word reading was assessed three times over 36 months in a large (N = 995) sample, including healthy control, AD, and Mild Cognitive Impairment (MCI) groups. At baseline, MCI and AD groups read correctly an average of 3.01 and 7.39 fewer words, respectively, than healthy controls. The MCI group�s performance remained stable during the study, but the AD group declined. Importantly, the observed decline was likely an underestimate, as significant numbers of the AD participants (42.6%) could not complete the task at follow-up. Use of alternate (e.g., demographics-based) methods is advised to augment or replace word pronunciation in estimating premorbid intelligence in individuals with even mild AD. © 2018 American Psychological Association.

U2 - 10.1037/pas0000565

DO - 10.1037/pas0000565

M3 - Article

JO - Psychological Assessment

JF - Psychological Assessment

SN - 1040-3590

ER -