Training surface and intensity : inflammation, hemolysis and hepcidin expression

Peter Peeling, Brian Dawson, C. Goodman, Grant Landers, E.T. Wiegerinck, D.W. Swinkels, Debbie Trinder

    Research output: Contribution to journalArticle

    75 Citations (Scopus)

    Abstract

    Purpose: This investigation assessed the effects of training intensity and ground surface type on hemolysis, inflammation, and hepcidin activity during running. Methods: Ten highly trained male endurance athletes completed a graded exercise test, two continuous 10-km runs on a grass (GRASS) and a bitumen road surface (ROAD) at 75%-80% peak V·O2 running velocity, and a 10 × 1-km interval running session (INT) at 90%-95% of the peak V·O2 running velocity. Venous blood and urine samples were collected before, immediately after, and at 3 and 24 h after exercise. Serum samples were analyzed for circulating levels of IL-6, free hemoglobin (Hb), haptoglobin (Hp), iron, and ferritin. Urine samples were analyzed for changes in hepcidin expression. Results: After running, the IL-6 and free Hb were significantly greater, and serum Hp was significantly lower than preexercise values in all three conditions (P <0.05). Furthermore, IL-6 levels and the change in free Hb from baseline were significantly greater in the INT compared with those in the GRASS (P <0.05). There were no differences between the GRASS and ROAD training surfaces (P > 0.05). Serum iron and ferritin were significantly increased after exercise in all three conditions (P <0.05) but were not different between trials. Conclusion: Greater running intensities incur more inflammation and hemolysis, but these variables were not affected by the surface type trained upon.
    Original languageEnglish
    Pages (from-to)1138-1145
    JournalMedicine & Science in Sports & Exercise
    Volume41
    Issue number5
    DOIs
    Publication statusPublished - 2009

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    Hepcidins
    Hemolysis
    Running
    Inflammation
    Haptoglobins
    asphalt
    Ferritins
    Interleukin-6
    Hemoglobins
    Iron
    Serum
    Urine
    Exercise
    Poaceae
    Exercise Test
    Athletes

    Cite this

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    title = "Training surface and intensity : inflammation, hemolysis and hepcidin expression",
    abstract = "Purpose: This investigation assessed the effects of training intensity and ground surface type on hemolysis, inflammation, and hepcidin activity during running. Methods: Ten highly trained male endurance athletes completed a graded exercise test, two continuous 10-km runs on a grass (GRASS) and a bitumen road surface (ROAD) at 75{\%}-80{\%} peak V·O2 running velocity, and a 10 × 1-km interval running session (INT) at 90{\%}-95{\%} of the peak V·O2 running velocity. Venous blood and urine samples were collected before, immediately after, and at 3 and 24 h after exercise. Serum samples were analyzed for circulating levels of IL-6, free hemoglobin (Hb), haptoglobin (Hp), iron, and ferritin. Urine samples were analyzed for changes in hepcidin expression. Results: After running, the IL-6 and free Hb were significantly greater, and serum Hp was significantly lower than preexercise values in all three conditions (P <0.05). Furthermore, IL-6 levels and the change in free Hb from baseline were significantly greater in the INT compared with those in the GRASS (P <0.05). There were no differences between the GRASS and ROAD training surfaces (P > 0.05). Serum iron and ferritin were significantly increased after exercise in all three conditions (P <0.05) but were not different between trials. Conclusion: Greater running intensities incur more inflammation and hemolysis, but these variables were not affected by the surface type trained upon.",
    author = "Peter Peeling and Brian Dawson and C. Goodman and Grant Landers and E.T. Wiegerinck and D.W. Swinkels and Debbie Trinder",
    year = "2009",
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    Training surface and intensity : inflammation, hemolysis and hepcidin expression. / Peeling, Peter; Dawson, Brian; Goodman, C.; Landers, Grant; Wiegerinck, E.T.; Swinkels, D.W.; Trinder, Debbie.

    In: Medicine & Science in Sports & Exercise, Vol. 41, No. 5, 2009, p. 1138-1145.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Training surface and intensity : inflammation, hemolysis and hepcidin expression

    AU - Peeling, Peter

    AU - Dawson, Brian

    AU - Goodman, C.

    AU - Landers, Grant

    AU - Wiegerinck, E.T.

    AU - Swinkels, D.W.

    AU - Trinder, Debbie

    PY - 2009

    Y1 - 2009

    N2 - Purpose: This investigation assessed the effects of training intensity and ground surface type on hemolysis, inflammation, and hepcidin activity during running. Methods: Ten highly trained male endurance athletes completed a graded exercise test, two continuous 10-km runs on a grass (GRASS) and a bitumen road surface (ROAD) at 75%-80% peak V·O2 running velocity, and a 10 × 1-km interval running session (INT) at 90%-95% of the peak V·O2 running velocity. Venous blood and urine samples were collected before, immediately after, and at 3 and 24 h after exercise. Serum samples were analyzed for circulating levels of IL-6, free hemoglobin (Hb), haptoglobin (Hp), iron, and ferritin. Urine samples were analyzed for changes in hepcidin expression. Results: After running, the IL-6 and free Hb were significantly greater, and serum Hp was significantly lower than preexercise values in all three conditions (P <0.05). Furthermore, IL-6 levels and the change in free Hb from baseline were significantly greater in the INT compared with those in the GRASS (P <0.05). There were no differences between the GRASS and ROAD training surfaces (P > 0.05). Serum iron and ferritin were significantly increased after exercise in all three conditions (P <0.05) but were not different between trials. Conclusion: Greater running intensities incur more inflammation and hemolysis, but these variables were not affected by the surface type trained upon.

    AB - Purpose: This investigation assessed the effects of training intensity and ground surface type on hemolysis, inflammation, and hepcidin activity during running. Methods: Ten highly trained male endurance athletes completed a graded exercise test, two continuous 10-km runs on a grass (GRASS) and a bitumen road surface (ROAD) at 75%-80% peak V·O2 running velocity, and a 10 × 1-km interval running session (INT) at 90%-95% of the peak V·O2 running velocity. Venous blood and urine samples were collected before, immediately after, and at 3 and 24 h after exercise. Serum samples were analyzed for circulating levels of IL-6, free hemoglobin (Hb), haptoglobin (Hp), iron, and ferritin. Urine samples were analyzed for changes in hepcidin expression. Results: After running, the IL-6 and free Hb were significantly greater, and serum Hp was significantly lower than preexercise values in all three conditions (P <0.05). Furthermore, IL-6 levels and the change in free Hb from baseline were significantly greater in the INT compared with those in the GRASS (P <0.05). There were no differences between the GRASS and ROAD training surfaces (P > 0.05). Serum iron and ferritin were significantly increased after exercise in all three conditions (P <0.05) but were not different between trials. Conclusion: Greater running intensities incur more inflammation and hemolysis, but these variables were not affected by the surface type trained upon.

    U2 - 10.1249/MSS.0b013e318192ce58

    DO - 10.1249/MSS.0b013e318192ce58

    M3 - Article

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    SP - 1138

    EP - 1145

    JO - Medicine & Science in Sports & Exercise

    JF - Medicine & Science in Sports & Exercise

    SN - 0195-9131

    IS - 5

    ER -