Tracheobronchitis in ulcerative colitis: A case report of therapeutic response with infliximab and review of the literature

Lisa Horgan, Siobhain Mulrennan, Lloyd D'Orsogna, Andrew McLean-Tooke

Research output: Contribution to journalReview article

Abstract

Background: The extra-intestinal manifestation of tracheobronchitis is a rare complication of ulcerative colitis (UC). Here, we present a case of UC-related tracheobronchitis wherein the positive clinical effects of infliximab are demonstrated. Case presentation: We report the case of a 39-year old woman who presented with a chronic productive cough on a distant background of surgically managed ulcerative colitis (UC). Our patient failed to achieve a satisfactory clinical improvement despite treatment with high dose inhaled corticosteroids, oral corticosteroids and azathioprine. Infliximab therapy was commenced and was demonstrated to achieve macroscopic and symptomatic remission of disease. Conclusions: We present the first case report documenting the benefits of infliximab in UC-related tracheobronchitis.

Original languageEnglish
Article number171
JournalBMC Gastroenterology
Volume19
Issue number1
DOIs
Publication statusPublished - 1 Nov 2019

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