Tissue Engineering of the Nervous System

Paul D. Dalton, Alan R. Harvey, Martin Oudega, Giles W. Plant

Research output: Chapter in Book/Conference paperChapterpeer-review

9 Citations (Scopus)


This chapter covers the challenges and approaches associated with tissue engineering (TE) in the peripheral and central nervous system. The molecular and cellular environment of each tissue demands particular emphasis, as do the natural anatomical structure and relevant animal models for repair. Given the complex interactions between neurons, glia, and the immune system in vivo, it is important to note that to date TE has only encompassed limited areas of neuroscience. The induction of neurite outgrowth and nerve regeneration has attracted the most attention, while materials for neuroprotection strategies have so far been more limited in their application.

Original languageEnglish
Title of host publicationTissue Engineering
Subtitle of host publicationSecond Edition
EditorsClemens A. van Blitterswijk, Jan de Boer
Place of PublicationUnited Kingdom
PublisherAcademic Press
Number of pages43
ISBN (Print)9780124201453
Publication statusPublished - 10 Dec 2014


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