Tissue ablation via optical fibre delivery of UVC laser radiation

J. Miller; X. Yu; Paula Yu; Stephen Cringle; Dao-Yi Yu

doi:10.1117/12.786035

Tissue ablation via optical fibre delivery of UVC laser radiation

J. Miller, X. Yu, Paula Yu, Stephen Cringle, Dao-Yi Yu

Research output: Contribution to journal › Article › peer-review

Abstract

We report the use of an ultraviolet (UV) laser and optical fibre arrangement capable of precise and controllable tissue ablation. The 5th (213nm) and 4th (266nm) harmonics of a Nd:YAG laser were launched into optical fibres using a hollow glass taper to concentrate the beam. Standard and modified silica/silica optical fibres were used, all commercially available. The available energy and fluence, as a function of optical fibre length, were evaluated and maximised. Single 5ns pulses were used to ablate both fresh porcine retina and in vivo rat trabecular meshwork. Fluences of 0.4 to 4.0 J/cm2 of 266nm and 0.2 to 1.0 J/cm2 of 213nm were used respectively. Thus demonstrating the potential use of this system for intraocular surgical applications.

Original language	English
Pages (from-to)	70043D-70043D-4
Journal	Optical Engineering
Volume	7004
Issue number	70043D
DOIs	https://doi.org/10.1117/12.786035
Publication status	Published - 2008

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title = "Tissue ablation via optical fibre delivery of UVC laser radiation",

abstract = "We report the use of an ultraviolet (UV) laser and optical fibre arrangement capable of precise and controllable tissue ablation. The 5th (213nm) and 4th (266nm) harmonics of a Nd:YAG laser were launched into optical fibres using a hollow glass taper to concentrate the beam. Standard and modified silica/silica optical fibres were used, all commercially available. The available energy and fluence, as a function of optical fibre length, were evaluated and maximised. Single 5ns pulses were used to ablate both fresh porcine retina and in vivo rat trabecular meshwork. Fluences of 0.4 to 4.0 J/cm2 of 266nm and 0.2 to 1.0 J/cm2 of 213nm were used respectively. Thus demonstrating the potential use of this system for intraocular surgical applications.",

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AU - Cringle, Stephen

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JF - Optical Engineering

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Tissue ablation via optical fibre delivery of UVC laser radiation

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