Timing of excision after a non-severe burn has a significant impact on the subsequent immune response in a murine model

Vanessa S. Fear; W.P. Poh; S. Valvis; Jason C. Waithman; Bree Foley; Fiona M. Wood; Mark W. Fear

doi:10.1016/j.burns.2016.01.013

Timing of excision after a non-severe burn has a significant impact on the subsequent immune response in a murine model

Vanessa S. Fear, W.P. Poh, S. Valvis, Jason C. Waithman, Bree Foley, Fiona M. Wood, Mark W. Fear

UWA Centre for Child Health Research (affiliated with the Telethon Kids Institute)

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

© 2016 Elsevier Ltd and ISBI. All rights reserved.Background Burn excision has emerged as the dominant clinical paradigm in treatment of deep burns. Surgical intervention is common but the timing of wound excision is a balance between wound depth assessment, avoidance of infection and unnecessary intervention. However the physiological impact of timing of excision and consequences for the immune response are not well understood. Methods Mice were subject to full-thickness burn (

Original language	English
Pages (from-to)	815-824
Number of pages	10
Journal	Burns
Volume	42
Issue number	4
DOIs	https://doi.org/10.1016/j.burns.2016.01.013
Publication status	Published - 1 Jun 2016

Access to Document

10.1016/j.burns.2016.01.013

Cite this

@article{3ce1b2a1ea6347e78b0605d406e5137d,

title = "Timing of excision after a non-severe burn has a significant impact on the subsequent immune response in a murine model",

abstract = "{\textcopyright} 2016 Elsevier Ltd and ISBI. All rights reserved.Background Burn excision has emerged as the dominant clinical paradigm in treatment of deep burns. Surgical intervention is common but the timing of wound excision is a balance between wound depth assessment, avoidance of infection and unnecessary intervention. However the physiological impact of timing of excision and consequences for the immune response are not well understood. Methods Mice were subject to full-thickness burn (",

author = "Fear, {Vanessa S.} and W.P. Poh and S. Valvis and Waithman, {Jason C.} and Bree Foley and Wood, {Fiona M.} and Fear, {Mark W.}",

year = "2016",

month = jun,

day = "1",

doi = "10.1016/j.burns.2016.01.013",

language = "English",

volume = "42",

pages = "815--824",

journal = "Burns",

issn = "0305-4179",

publisher = "Elsevier",

number = "4",

}

TY - JOUR

T1 - Timing of excision after a non-severe burn has a significant impact on the subsequent immune response in a murine model

AU - Fear, Vanessa S.

AU - Poh, W.P.

AU - Valvis, S.

AU - Waithman, Jason C.

AU - Foley, Bree

AU - Wood, Fiona M.

AU - Fear, Mark W.

PY - 2016/6/1

Y1 - 2016/6/1

N2 - © 2016 Elsevier Ltd and ISBI. All rights reserved.Background Burn excision has emerged as the dominant clinical paradigm in treatment of deep burns. Surgical intervention is common but the timing of wound excision is a balance between wound depth assessment, avoidance of infection and unnecessary intervention. However the physiological impact of timing of excision and consequences for the immune response are not well understood. Methods Mice were subject to full-thickness burn (

AB - © 2016 Elsevier Ltd and ISBI. All rights reserved.Background Burn excision has emerged as the dominant clinical paradigm in treatment of deep burns. Surgical intervention is common but the timing of wound excision is a balance between wound depth assessment, avoidance of infection and unnecessary intervention. However the physiological impact of timing of excision and consequences for the immune response are not well understood. Methods Mice were subject to full-thickness burn (

U2 - 10.1016/j.burns.2016.01.013

DO - 10.1016/j.burns.2016.01.013

M3 - Article

C2 - 26880298

VL - 42

SP - 815

EP - 824

JO - Burns

JF - Burns

SN - 0305-4179

IS - 4

ER -

Timing of excision after a non-severe burn has a significant impact on the subsequent immune response in a murine model

Abstract

Access to Document

Fingerprint

Cite this