Three-way interaction of neuroticism, extraversion, and conscientiousness in the internalizing disorders: Evidence of disorder specificity in a psychiatric sample

Kristin Naragon-Gainey, Leonard J. Simms

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

It is well-established that neuroticism, extraversion, and conscientiousness are individually associated with internalizing disorders, but research suggests that these main effects may be qualified by a three-way interaction when predicting depression. The current study was the first to examine this three-way interaction in a psychiatric sample (N = 463) with a range of internalizing symptoms as the outcomes. Using two omnibus personality inventories and a diagnostic interview, the expected three-way interaction emerged most consistently for symptoms of major depression, and there was also evidence of synergistic effects for post-traumatic stress disorder and generalized anxiety disorder. Findings indicate that, even in a clinically-distressed and currently-disordered sample, high levels of extraversion and conscientiousness protect against distress disorders for those with high levels of neuroticism.

Original languageEnglish
Pages (from-to)16-26
Number of pages11
JournalJournal of Research in Personality
Volume70
DOIs
Publication statusPublished - Oct 2017
Externally publishedYes

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