Abstract
Four C-C bonds, four rings, and eight contiguous stereocenters in one go! Tetracyclic product 2, which results on warming simple acyclic precursor 1 with a mild Lewis acid, is formed through an efficient and highly stereoselective domino sequence of two intramolecular Diels-Alder reactions. Pharmacologically important norsteroids are just one potential application of this extremely effective approach to fused polycyclic systems.
| Original language | English |
|---|---|
| Pages (from-to) | 4074-4076 |
| Number of pages | 3 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 40 |
| Issue number | 21 |
| DOIs | |
| Publication status | Published - 5 Nov 2001 |
| Externally published | Yes |