The use of biochemical markers of bone turnover in the clinical management of primary and secondary osteoporosis

Samuel D. Vasikaran; Paul Chubb

doi:10.1007/s12020-016-0900-2

The use of biochemical markers of bone turnover in the clinical management of primary and secondary osteoporosis

Samuel D. Vasikaran, Paul Chubb

Research output: Contribution to journal › Article

21 Citations (Scopus)

Abstract

© 2016, Springer Science+Business Media New York. The purpose of the present study was to examine of the current role of bone turnover markers (BTMs) in the management of osteoporosis. Perusal of the literature examines the available evidence for the utility of BTMs for decision to treat and for the monitoring of treatment for osteoporosis. There is no evidence for the use of BTMs for fracture risk calculation, decision to treat or for treatment selection. A very abnormal BTM value may be a clue to the presence of bone pathology other than uncomplicated osteoporosis. Whilst changes to BTMs following various osteoporosis treatments are well defined, their utility in monitoring individual patients has been less well established. Some fracture outcome-based data exist for the use of u-NTX target of

Original language	English
Pages (from-to)	222-225
Number of pages	4
Journal	Endocrine
Volume	52
Issue number	2
DOIs	https://doi.org/10.1007/s12020-016-0900-2
Publication status	Published - 2016

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abstract = "{\textcopyright} 2016, Springer Science+Business Media New York. The purpose of the present study was to examine of the current role of bone turnover markers (BTMs) in the management of osteoporosis. Perusal of the literature examines the available evidence for the utility of BTMs for decision to treat and for the monitoring of treatment for osteoporosis. There is no evidence for the use of BTMs for fracture risk calculation, decision to treat or for treatment selection. A very abnormal BTM value may be a clue to the presence of bone pathology other than uncomplicated osteoporosis. Whilst changes to BTMs following various osteoporosis treatments are well defined, their utility in monitoring individual patients has been less well established. Some fracture outcome-based data exist for the use of u-NTX target of",

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