The role of Vitamin B12 in the critically ill - A review

M. Romain; S. Sviri; D.M. M. Linton; I. Stav; Peter V. van Heerden

The role of Vitamin B12 in the critically ill - A review

M. Romain, S. Sviri, D.M. M. Linton, I. Stav, Peter V. van Heerden

Research output: Contribution to journal › Review article

Abstract

Vitamin B12 is an essential micronutrient, as humans have no capacity to produce the vitamin and it needs to be ingested from animal proteins. The ingested Vitamin B12 undergoes a complex process of absorption and assimilation. Vitamin B12 is essential for cellular function. Deficiency affects 15% of patients older than 65 and results in haematological and neurological disorders. Low levels of Vitamin B12 may also be an independent risk factor for coronary artery disease. High levels of Vitamin B12 are associated with inflammation and represent a poor outlook for critically ill patients. Treatment of Vitamin B12 deficiency is simple, but may be lifelong.

Original language	English
Pages (from-to)	447-452
Number of pages	6
Journal	Anaesthesia and Intensive Care
Volume	44
Issue number	4
Publication status	Published - Jul 2016
Externally published	Yes

Cite this

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title = "The role of Vitamin B12 in the critically ill - A review",

abstract = "Vitamin B12 is an essential micronutrient, as humans have no capacity to produce the vitamin and it needs to be ingested from animal proteins. The ingested Vitamin B12 undergoes a complex process of absorption and assimilation. Vitamin B12 is essential for cellular function. Deficiency affects 15% of patients older than 65 and results in haematological and neurological disorders. Low levels of Vitamin B12 may also be an independent risk factor for coronary artery disease. High levels of Vitamin B12 are associated with inflammation and represent a poor outlook for critically ill patients. Treatment of Vitamin B12 deficiency is simple, but may be lifelong.",

author = "M. Romain and S. Sviri and Linton, {D.M. M.} and I. Stav and {van Heerden}, {Peter V.}",

year = "2016",

month = jul,

language = "English",

volume = "44",

pages = "447--452",

journal = "Anaesthesia Intensive Care",

issn = "0310-057X",

publisher = "Australian Society of Anaesthetists",

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T1 - The role of Vitamin B12 in the critically ill - A review

AU - Romain, M.

AU - Sviri, S.

AU - Linton, D.M. M.

AU - Stav, I.

AU - van Heerden, Peter V.

PY - 2016/7

Y1 - 2016/7

N2 - Vitamin B12 is an essential micronutrient, as humans have no capacity to produce the vitamin and it needs to be ingested from animal proteins. The ingested Vitamin B12 undergoes a complex process of absorption and assimilation. Vitamin B12 is essential for cellular function. Deficiency affects 15% of patients older than 65 and results in haematological and neurological disorders. Low levels of Vitamin B12 may also be an independent risk factor for coronary artery disease. High levels of Vitamin B12 are associated with inflammation and represent a poor outlook for critically ill patients. Treatment of Vitamin B12 deficiency is simple, but may be lifelong.

AB - Vitamin B12 is an essential micronutrient, as humans have no capacity to produce the vitamin and it needs to be ingested from animal proteins. The ingested Vitamin B12 undergoes a complex process of absorption and assimilation. Vitamin B12 is essential for cellular function. Deficiency affects 15% of patients older than 65 and results in haematological and neurological disorders. Low levels of Vitamin B12 may also be an independent risk factor for coronary artery disease. High levels of Vitamin B12 are associated with inflammation and represent a poor outlook for critically ill patients. Treatment of Vitamin B12 deficiency is simple, but may be lifelong.

M3 - Review article

VL - 44

SP - 447

EP - 452

JO - Anaesthesia Intensive Care

JF - Anaesthesia Intensive Care

SN - 0310-057X

IS - 4

ER -

The role of Vitamin B12 in the critically ill - A review

Abstract

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