Abstract
Polycystic ovary syndrome (PCOS) is a common endocrine disease that causes infertility in women of reproductive age. An excessive level of androgen and obesity are recognised as causes of PCOS, yet the precise mechanism of PCOS remains unclear. Kisspeptin neurons located in the arcuate nucleus are known to regulate gonadotropin-releasing hormone pulses, and may play a role in the disease. To determine the impact of androgen signalling and diet on the hypothalamic characteristics of PCOS, we examined expression of key neuropeptides that regulate kisspeptin in two PCOS mouse models.
| Original language | English |
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| Qualification | Masters |
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| Award date | 6 Nov 2020 |
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| Publication status | Unpublished - 2020 |
Access to Document
- THESIS - MASTER BY RESEARCH - MOTOOKA, Shima - 2020
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