The role of dopamine gene variation and error detection in predicting impulsivity

Jasmine Belinda Taylor

Research output: ThesisDoctoral Thesis

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Abstract

The mechanisms underlying impulsive behaviour in the general population remain largely unknown. Previous studies have postulated that catecholamine gene variation and a neurocognitive component process, known as error monitoring, give rise to such individual differences. This thesis examines the interrelationships between genes, error monitoring, and impulsivity
in humans. Based on findings throughout, a mediation model is proposed between the dopamine D2 receptor gene, an electrophysiological index of error monitoring called the error-related negativity, and specific facets of impulsivity. Results suggest event-related potentials may provide a more proximal measure of gene function than behaviour and highlight the multidimensional nature of impulsivity.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Supervisors/Advisors
  • Visser, Troy, Supervisor
  • Fox, Allison, Supervisor
  • Bellgrove, Mark A., Supervisor, External person
Thesis sponsors
Award date13 Jul 2018
DOIs
Publication statusUnpublished - 2018

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