The prevention of wound infection in patients undergoing colorectal surgery

Cameron Platell, John Hall

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


Colorectal operations are, at best, clean-contaminated procedures, and at times there is gross contamination of both the peritoneal cavity and the surfaces of the surgical wound. In addition, the diseases of the large bowel that require surgery tend to afflict elderly patients. Collectively, the combination of an unclean environment, major surgery and debilitated patients creates a situation that is associated with a very high incidence of wound infection. This review documents the considerable support from clinical trials and meta-analyses that exists for the prophylactic use of a single dose of a suitable parenteral anti-microbial agent. In addition, although the evidence is less clear cut, it does not appear that the use of mechanical bowel preparations reduces the incidence of wound infections after colorectal surgery. (C) 2001 The Hospital Infection Society
Original languageEnglish
Pages (from-to)233-238
JournalJournal of Hospital Infection
Issue number4
Publication statusPublished - 2001


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