| Original language | English |
|---|---|
| Patent number | WO 2021/24810 A1 |
| Publication status | Published - 2021 |
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Kuthubutheen, J., Mooranian, A., Brown, D., & Al-Salami, H. (2021). The present invention relates to methods for preventing, reducing, or treating the incidence and/or severity of a disorder caused by stress-induced cellular damage in the ear of a subject, such as vestibular disorders, hearing impairment, and conditions related to hair cell degeneration or death. Specifically, this invention pertains to formulations comprising probucol or a probucol ester, a bioavailability-enhancing compound comprising a bile acid, and optionally a carrier. The administration of these formulations can treat hearing loss and/or hair cell degeneration or death. (Patent No. WO 2021/24810 A1).
Kuthubutheen, Jafri (Inventor) ; Mooranian, Armin (Inventor) ; Brown, Daniel (Inventor) et al. / The present invention relates to methods for preventing, reducing, or treating the incidence and/or severity of a disorder caused by stress-induced cellular damage in the ear of a subject, such as vestibular disorders, hearing impairment, and conditions related to hair cell degeneration or death. Specifically, this invention pertains to formulations comprising probucol or a probucol ester, a bioavailability-enhancing compound comprising a bile acid, and optionally a carrier. The administration of these formulations can treat hearing loss and/or hair cell degeneration or death. Patent No.: WO 2021/24810 A1.
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title = "The present invention relates to methods for preventing, reducing, or treating the incidence and/or severity of a disorder caused by stress-induced cellular damage in the ear of a subject, such as vestibular disorders, hearing impairment, and conditions related to hair cell degeneration or death. Specifically, this invention pertains to formulations comprising probucol or a probucol ester, a bioavailability-enhancing compound comprising a bile acid, and optionally a carrier. The administration of these formulations can treat hearing loss and/or hair cell degeneration or death.",
author = "Jafri Kuthubutheen and Armin Mooranian and Daniel Brown and Hani Al-Salami",
year = "2021",
language = "English",
type = "Patent",
note = "WO 2021/24810 A1",
}
Kuthubutheen, J, Mooranian, A, Brown, D & Al-Salami, H, The present invention relates to methods for preventing, reducing, or treating the incidence and/or severity of a disorder caused by stress-induced cellular damage in the ear of a subject, such as vestibular disorders, hearing impairment, and conditions related to hair cell degeneration or death. Specifically, this invention pertains to formulations comprising probucol or a probucol ester, a bioavailability-enhancing compound comprising a bile acid, and optionally a carrier. The administration of these formulations can treat hearing loss and/or hair cell degeneration or death., Patent No. WO 2021/24810 A1.
The present invention relates to methods for preventing, reducing, or treating the incidence and/or severity of a disorder caused by stress-induced cellular damage in the ear of a subject, such as vestibular disorders, hearing impairment, and conditions related to hair cell degeneration or death. Specifically, this invention pertains to formulations comprising probucol or a probucol ester, a bioavailability-enhancing compound comprising a bile acid, and optionally a carrier. The administration of these formulations can treat hearing loss and/or hair cell degeneration or death. / Kuthubutheen, Jafri (Inventor); Mooranian, Armin (Inventor); Brown, Daniel (Inventor) et al.
Patent No.: WO 2021/24810 A1.
Patent No.: WO 2021/24810 A1.
Research output: Patent › peer-review
TY - PAT
T1 - The present invention relates to methods for preventing, reducing, or treating the incidence and/or severity of a disorder caused by stress-induced cellular damage in the ear of a subject, such as vestibular disorders, hearing impairment, and conditions related to hair cell degeneration or death. Specifically, this invention pertains to formulations comprising probucol or a probucol ester, a bioavailability-enhancing compound comprising a bile acid, and optionally a carrier. The administration of these formulations can treat hearing loss and/or hair cell degeneration or death.
AU - Kuthubutheen, Jafri
AU - Mooranian, Armin
AU - Brown, Daniel
AU - Al-Salami, Hani
PY - 2021
Y1 - 2021
M3 - Patent
M1 - WO 2021/24810 A1
ER -
Kuthubutheen J, Mooranian A, Brown D, Al-Salami H, inventors. The present invention relates to methods for preventing, reducing, or treating the incidence and/or severity of a disorder caused by stress-induced cellular damage in the ear of a subject, such as vestibular disorders, hearing impairment, and conditions related to hair cell degeneration or death. Specifically, this invention pertains to formulations comprising probucol or a probucol ester, a bioavailability-enhancing compound comprising a bile acid, and optionally a carrier. The administration of these formulations can treat hearing loss and/or hair cell degeneration or death. WO 2021/24810 A1. 2021.