The preparation of poly(2-hydroxyethyl methacrylate) and poly {(2-hydroxyethyl methacrylate)-co-[poly(ethylene glycol) methyl ether methacrylate]} by photoinitiated polymerisation-induced phase seperation in water

Murray Baker, David Brown, Ylenia Casadio, T.V. Chirila

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)

Abstract

This paper describes the application of a photoinitiated polymerisation-induced phase separation method to the preparation of PHEMA and P[HEMA-co-(MeO-PEGMA)] hydrogels. PHEMA sponges having a morphology of agglomerated polymer droplets and interconnected pores were easily prepared from aqueous mixtures containing HEMA, EDGMA (crosslinker) and DPAP (photoinitiator). P[HEMA-co-(MeOPEGMA)] copolymers having similar morphologies could also be prepared, provided that the proportion of MeO-PEGMA in the copolymer was relatively small. When higher proportions of MeO-PEGMA were used, the resulting polymers were gels rather than sponges, and did not show the sought after droplet/ pore morphology. P[HEMA-co-(MeO-PEGMA)] copolymers having higher proportions of MeO-PEGMA and having a morphology of agglomerated polymer droplets and interconnected pores were easily prepared by addition of NaCl to the polymerisation mixture. Thus, incorporation of MeO-PEGMA and adddition of NaCl to the photopolymerisation mixtures provides an easy way of tuning the hydrophilicity of PHEMA copolymer sponges without compromising the desired porous morphology. ©2009 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)5918-5927
JournalPolymer
Volume50
Issue number25
DOIs
Publication statusPublished - 2009

Fingerprint

Dive into the research topics of 'The preparation of poly(2-hydroxyethyl methacrylate) and poly {(2-hydroxyethyl methacrylate)-co-[poly(ethylene glycol) methyl ether methacrylate]} by photoinitiated polymerisation-induced phase seperation in water'. Together they form a unique fingerprint.

Cite this