The population-based prevalence of albuminuria in children

Nicholas Larkins, Armando Teixeira-Pinto, Jonathan Craig

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

OBJECTIVES: To determine the population-based prevalence of albuminuria in Australian children and validate any negative correlation with body mass index (BMI).

METHODS: Data from the Australian Health Survey 2011-2013 were used. This is a large-scale survey of the health of the Australian population, conducted by the Australian Bureau of Statistics, and uses a stratified, multistage area design with replicate weights attached to observations to allow for the derivation of accurate population estimates. We considered children aged 5-18 years, and defined albuminuria as an albumin-to-creatinine ratio (ACR) >30 mg/g (3.4 mg/mmol).

RESULTS: A total of 975 children provided urine samples for determination of ACR. The prevalence of albuminuria was 10.2% for males (95% confidence interval [CI] 6.1-14.2) and 15.5% for females (95% CI 10.7-20.3). After adjusting for age and gender, the odds ratio for albuminuria associated with being overweight or obese was 0.34 (95% CI 0.15-0.75). This relationship also held for waist-to-height ratio, where the adjusted odds ratio for each 0.1 increase was 0.46 (95% CI 0.26-0.82).

CONCLUSIONS: Albuminuria, using a measurement suitable for population-based and clinical screening, occurs in 12.8% of school-aged Australian children, and is less common in overweight and obese children.

Original languageEnglish
Pages (from-to)2303-2309
JournalPediatric Nephrology
Volume32
Issue number12
DOIs
Publication statusPublished - Dec 2017
Externally publishedYes

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Albuminuria
Confidence Intervals
Population
Health Surveys
Albumins
Creatinine
Odds Ratio
Body Mass Index
Urine
Weights and Measures

Cite this

Larkins, Nicholas ; Teixeira-Pinto, Armando ; Craig, Jonathan. / The population-based prevalence of albuminuria in children. In: Pediatric Nephrology. 2017 ; Vol. 32, No. 12. pp. 2303-2309.
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The population-based prevalence of albuminuria in children. / Larkins, Nicholas; Teixeira-Pinto, Armando; Craig, Jonathan.

In: Pediatric Nephrology, Vol. 32, No. 12, 12.2017, p. 2303-2309.

Research output: Contribution to journalArticle

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N2 - OBJECTIVES: To determine the population-based prevalence of albuminuria in Australian children and validate any negative correlation with body mass index (BMI).METHODS: Data from the Australian Health Survey 2011-2013 were used. This is a large-scale survey of the health of the Australian population, conducted by the Australian Bureau of Statistics, and uses a stratified, multistage area design with replicate weights attached to observations to allow for the derivation of accurate population estimates. We considered children aged 5-18 years, and defined albuminuria as an albumin-to-creatinine ratio (ACR) >30 mg/g (3.4 mg/mmol).RESULTS: A total of 975 children provided urine samples for determination of ACR. The prevalence of albuminuria was 10.2% for males (95% confidence interval [CI] 6.1-14.2) and 15.5% for females (95% CI 10.7-20.3). After adjusting for age and gender, the odds ratio for albuminuria associated with being overweight or obese was 0.34 (95% CI 0.15-0.75). This relationship also held for waist-to-height ratio, where the adjusted odds ratio for each 0.1 increase was 0.46 (95% CI 0.26-0.82).CONCLUSIONS: Albuminuria, using a measurement suitable for population-based and clinical screening, occurs in 12.8% of school-aged Australian children, and is less common in overweight and obese children.

AB - OBJECTIVES: To determine the population-based prevalence of albuminuria in Australian children and validate any negative correlation with body mass index (BMI).METHODS: Data from the Australian Health Survey 2011-2013 were used. This is a large-scale survey of the health of the Australian population, conducted by the Australian Bureau of Statistics, and uses a stratified, multistage area design with replicate weights attached to observations to allow for the derivation of accurate population estimates. We considered children aged 5-18 years, and defined albuminuria as an albumin-to-creatinine ratio (ACR) >30 mg/g (3.4 mg/mmol).RESULTS: A total of 975 children provided urine samples for determination of ACR. The prevalence of albuminuria was 10.2% for males (95% confidence interval [CI] 6.1-14.2) and 15.5% for females (95% CI 10.7-20.3). After adjusting for age and gender, the odds ratio for albuminuria associated with being overweight or obese was 0.34 (95% CI 0.15-0.75). This relationship also held for waist-to-height ratio, where the adjusted odds ratio for each 0.1 increase was 0.46 (95% CI 0.26-0.82).CONCLUSIONS: Albuminuria, using a measurement suitable for population-based and clinical screening, occurs in 12.8% of school-aged Australian children, and is less common in overweight and obese children.

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