The Plant Mitochondrial Transportome: Balancing Metabolic Demands with Energetic Constraints.

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

In plants, mitochondrial function is associated with hundreds of metabolic reactions. To facilitate these reactions, charged substrates and cofactors move across the charge-impermeable inner mitochondrial membrane via specialized transporters and must work cooperatively with the electrochemical gradient which is essential for mitochondrial function. The regulatory framework for mitochondrial metabolite transport is expected to be more complex in plants than in mammals owing to the close metabolic association between mitochondrial, plastids, and peroxisome metabolism, as well as to the major diurnal fluctuations in plant metabolic function. We propose here how recent advances can be integrated towards defining the mitochondrial transportome in plants. We also discuss what this reveals about sustaining cooperativity between bioenergetics, metabolism, and transport in typical and challenging environments.
Original languageEnglish
Pages (from-to)662-676
Number of pages15
JournalTrends in Plant Science
Volume21
Issue number8
DOIs
Publication statusPublished - Aug 2016

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metabolism
peroxisomes
diurnal variation
energy metabolism
plastids
transporters
mammals
metabolites
mitochondrial membrane

Cite this

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title = "The Plant Mitochondrial Transportome: Balancing Metabolic Demands with Energetic Constraints.",
abstract = "In plants, mitochondrial function is associated with hundreds of metabolic reactions. To facilitate these reactions, charged substrates and cofactors move across the charge-impermeable inner mitochondrial membrane via specialized transporters and must work cooperatively with the electrochemical gradient which is essential for mitochondrial function. The regulatory framework for mitochondrial metabolite transport is expected to be more complex in plants than in mammals owing to the close metabolic association between mitochondrial, plastids, and peroxisome metabolism, as well as to the major diurnal fluctuations in plant metabolic function. We propose here how recent advances can be integrated towards defining the mitochondrial transportome in plants. We also discuss what this reveals about sustaining cooperativity between bioenergetics, metabolism, and transport in typical and challenging environments.",
author = "Lee, {Chun Pong} and Millar, {A. Harvey}",
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The Plant Mitochondrial Transportome: Balancing Metabolic Demands with Energetic Constraints. / Lee, Chun Pong; Millar, A. Harvey.

In: Trends in Plant Science, Vol. 21, No. 8, 08.2016, p. 662-676.

Research output: Contribution to journalReview article

TY - JOUR

T1 - The Plant Mitochondrial Transportome: Balancing Metabolic Demands with Energetic Constraints.

AU - Lee, Chun Pong

AU - Millar, A. Harvey

PY - 2016/8

Y1 - 2016/8

N2 - In plants, mitochondrial function is associated with hundreds of metabolic reactions. To facilitate these reactions, charged substrates and cofactors move across the charge-impermeable inner mitochondrial membrane via specialized transporters and must work cooperatively with the electrochemical gradient which is essential for mitochondrial function. The regulatory framework for mitochondrial metabolite transport is expected to be more complex in plants than in mammals owing to the close metabolic association between mitochondrial, plastids, and peroxisome metabolism, as well as to the major diurnal fluctuations in plant metabolic function. We propose here how recent advances can be integrated towards defining the mitochondrial transportome in plants. We also discuss what this reveals about sustaining cooperativity between bioenergetics, metabolism, and transport in typical and challenging environments.

AB - In plants, mitochondrial function is associated with hundreds of metabolic reactions. To facilitate these reactions, charged substrates and cofactors move across the charge-impermeable inner mitochondrial membrane via specialized transporters and must work cooperatively with the electrochemical gradient which is essential for mitochondrial function. The regulatory framework for mitochondrial metabolite transport is expected to be more complex in plants than in mammals owing to the close metabolic association between mitochondrial, plastids, and peroxisome metabolism, as well as to the major diurnal fluctuations in plant metabolic function. We propose here how recent advances can be integrated towards defining the mitochondrial transportome in plants. We also discuss what this reveals about sustaining cooperativity between bioenergetics, metabolism, and transport in typical and challenging environments.

U2 - 10.1016/j.tplants.2016.04.003

DO - 10.1016/j.tplants.2016.04.003

M3 - Review article

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JO - Trends in Plant Science

JF - Trends in Plant Science

SN - 1360-1385

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