The pathophysiology and the therapeutic potential of cannabinoids in prostate cancer

Kanika Singh, Nazim Nassar, Ava Bachari, Ellen Schanknecht, Srinivasareddy Telukutla, Roby Zomer, Terrence J. Piva, Nitin Mantri

Research output: Contribution to journalReview articlepeer-review

5 Citations (Scopus)

Abstract

Prostate cancer is the second most frequently occurring cancer diagnosed among males. Recent preclinical evidence implicates cannabinoids as powerful regulators of cell growth and differentiation. In this review, we focused on studies that demonstrated anticancer effects of cannabinoids and their possible mechanisms of action in prostate cancer. Besides the palliative effects of cannabinoids, research from the past two decades has demonstrated their promising potential as antitumor agents in a wide variety of cancers. This analysis may provide pharmacological insights into the selection of specific cannabinoids for the development of antitumor drugs for the treatment of prostate cancer.

Original languageEnglish
Article number4107
JournalCancers
Volume13
Issue number16
DOIs
Publication statusPublished - 2 Aug 2021

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