The Massigui region is located in the western Paleoproterozoic Baoulé-Mossi domain close to the Archean Kenema-Man domain, Man Shield, West African Craton, which is an ideal place for studying their amalgamation. The Massigui region consists of volcano-sedimentary sequences intruded by granitoid and dioritoid bodies and is transected by the large NE-SW Banifing Shear Zone. Metamorphism reached upper greenschist facies, locally amphibolite facies. Four tectonic phases have been recorded. The isoclinal folding D1 and transpressive D2 deformations correspond to the formation and the displacement along the Banifing Shear Zone that occurred during the deposition of the volcano-sedimentary sequences and the emplacement of most granitoids. Brittle-ductile deformation D3 participated in the structuration of the area while post-Eburnean D4 brittle deformation had only minor effects. Zircon SHRIMP U-Pb ages of granitoids and dioritoids indicate a major period of magmatic activity at c. 2100 Ma (Massigui quartz monzodiorite: 2112 ± 5 Ma, granodiorite: 2103 ± 5 Ma, pink quartz monzonite: 2095 ± 9 Ma; Syobougou quartz microdiorite: 2102 ± 10 Ma; Tiéfala foliated quartz micromonzodiorite: 2106 ± 11 Ma). SHRIMP U-Pb ages of detrital zircons show that the sources of the sediment are exclusively Birimian, with three well-defined detrital ages at 2125 ± 8 Ma (22% zircons), 2148 ± 6 Ma (28%) and 2215 ± 13 Ma (14%). Major and trace elements indicate that the dioritic intrusions belong to a medium-K sequence showing rapid K enrichment announcing the magmatic emplacement of the high-K calc-alkaline granitoids that form most of the Massigui batholiths. The proposed regional model includes: (1) >2125 Ma oceanic plate subduction towards the E below the Baoulé-Mossi Birimian segment; (2) 2125–2090 Ma oblique continental subduction of the Archean Kenema-Man craton (closure of the Birimian ocean, collision stage), major movements along the Banifing shear zone, magmatism and volcano-sedimentary deposition in the Massigui region; (3) 2090–2020 Ma metacratonization of the subducting Kenema-Man craton generating the emplacement of magmas with Archean protoliths, a main difference with the Baoulé-Mossi juvenile granitoids. Paleomagnetic data, similar lithologies and ages suggest that the Kenema-Man craton was a part of the Sarmatia craton, tying the geotectonic evolution of the region to the Columbia supercontinent amalgamation.