This thesis describes the development of new nickel(0) and nickel(II) complexes containing both N-heterocyclic carbene and phosphite ligands. New three-coordinate nickel(0) complexes were shown to be highly capable catalysts for the Suzuki-Miyaura cross-coupling of aryl tosylates with boronic acids. Mechanistic details of this reaction were elucidated by the isolation and characterisation of a reaction intermediate as well as through NMR studies. Also explored in the thesis is the application of tert-butyldimethylsilyl amine as an effective silylating agent for phenols, benzyl alcohols and carboxylic acids under mild and solvent-free conditions.
|Qualification||Doctor of Philosophy|
|Award date||22 Feb 2021|
|Publication status||Unpublished - 2021|