During pregnancy, maternal inflammation and gut microbial dysbiosis may have lasting implications for the mother and her child. The work of this thesis investigated the influence of antenatal dietary fibre sub-type intakes on maternal and infant metabolic and immune health. Higher maternal consumption of resistant starch was associated with reduced doctor-diagnosed infant wheeze. In overweight/obese women, consumption of prebiotic fibre supplementation also lowered the incidence of gestational diabetes mellitus. This supports a role of maternal dietary interventions for reducing the burden of immune and metabolic diseases and future studies to further delineate the effects on microbiome composition and microbial metabolites.
|Qualification||Doctor of Philosophy|
|Award date||29 Mar 2022|
|Publication status||Unpublished - 2022|