The impact of in utero and early life factors on the respiratory health of young adults - 24 year review of the Perth infant asthma follow-up study

Louisa Mary Owens

Research output: ThesisDoctoral Thesis

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Abstract

Many chronic respiratory Illnesses have origins very early in life. Hence, the Perth Infant Asthma Follow-up (PIAF) cohort was established with repeated longitudinal assessments of lung function and respiratory symptoms being made from early infancy to late adolescence. For this thesis, a 24 year follow-up was done to extend assessments to cover the entire post-natal lung growth period. The aim of the thesis was to identify in utero and early factors predictive of respiratory health in adulthood. In utero tobacco exposure, reduced lung function in infancy, early atopy and asthma were all associated with adverse respiratory outcomes in adulthood.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Award date19 Mar 2019
DOIs
Publication statusUnpublished - 2019

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Young Adult
Asthma
Lung
Health
Tobacco
Chronic Disease
Growth

Cite this

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AB - Many chronic respiratory Illnesses have origins very early in life. Hence, the Perth Infant Asthma Follow-up (PIAF) cohort was established with repeated longitudinal assessments of lung function and respiratory symptoms being made from early infancy to late adolescence. For this thesis, a 24 year follow-up was done to extend assessments to cover the entire post-natal lung growth period. The aim of the thesis was to identify in utero and early factors predictive of respiratory health in adulthood. In utero tobacco exposure, reduced lung function in infancy, early atopy and asthma were all associated with adverse respiratory outcomes in adulthood.

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