The impact of in utero and early life factors on the respiratory health of young adults - 24 year review of the Perth infant asthma follow-up study

Louisa Mary Owens

doi:10.26182/5cca3b5afb354

The impact of in utero and early life factors on the respiratory health of young adults - 24 year review of the Perth infant asthma follow-up study

Louisa Mary Owens

UWA Medical School

Research output: Thesis › Doctoral Thesis

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Abstract

Many chronic respiratory Illnesses have origins very early in life. Hence, the Perth Infant Asthma Follow-up (PIAF) cohort was established with repeated longitudinal assessments of lung function and respiratory symptoms being made from early infancy to late adolescence. For this thesis, a 24 year follow-up was done to extend assessments to cover the entire post-natal lung growth period. The aim of the thesis was to identify in utero and early factors predictive of respiratory health in adulthood. In utero tobacco exposure, reduced lung function in infancy, early atopy and asthma were all associated with adverse respiratory outcomes in adulthood.

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	The University of Western Australia
Supervisors/Advisors	Zhang, Brad, Supervisor Goldblatt, Jack, Supervisor Laing, Ingrid, Supervisor Le Souef, Peter, Supervisor
Award date	19 Mar 2019
DOIs	https://doi.org/10.26182/5cca3b5afb354
Publication status	Unpublished - 2019

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THESIS - DOCTOR OF PHILOSOPHY - OWENS Louisa Mary - 2019
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Cite this

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title = "The impact of in utero and early life factors on the respiratory health of young adults - 24 year review of the Perth infant asthma follow-up study",

abstract = "Many chronic respiratory Illnesses have origins very early in life. Hence, the Perth Infant Asthma Follow-up (PIAF) cohort was established with repeated longitudinal assessments of lung function and respiratory symptoms being made from early infancy to late adolescence. For this thesis, a 24 year follow-up was done to extend assessments to cover the entire post-natal lung growth period. The aim of the thesis was to identify in utero and early factors predictive of respiratory health in adulthood. In utero tobacco exposure, reduced lung function in infancy, early atopy and asthma were all associated with adverse respiratory outcomes in adulthood. ",

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AB - Many chronic respiratory Illnesses have origins very early in life. Hence, the Perth Infant Asthma Follow-up (PIAF) cohort was established with repeated longitudinal assessments of lung function and respiratory symptoms being made from early infancy to late adolescence. For this thesis, a 24 year follow-up was done to extend assessments to cover the entire post-natal lung growth period. The aim of the thesis was to identify in utero and early factors predictive of respiratory health in adulthood. In utero tobacco exposure, reduced lung function in infancy, early atopy and asthma were all associated with adverse respiratory outcomes in adulthood.

KW - Longitudinal Lung Function

KW - Infant

KW - Birth cohort

U2 - 10.26182/5cca3b5afb354

DO - 10.26182/5cca3b5afb354

M3 - Doctoral Thesis

ER -

The impact of in utero and early life factors on the respiratory health of young adults - 24 year review of the Perth infant asthma follow-up study

Abstract

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