The IASLC/ITMIG thymic epithelial tumors staging project: Proposal for an evidence-based stage classification system for the forthcoming (8th) edition of the TNM classification of malignant tumors

F.C. Detterbeck, K.L. Stratton, D.J. Giroux, H. Asamura, J.J. Crowley, C.B. Falkson, P.L. Filosso, A.A. Frazier, G. Giaccone, J. Huang, J. Kim, K. Kondo, M. Lucchi, M. Marino, E.M. Marom, A.G. Nicholson, M. Okumura, E. Ruffini, P. Van Schil, P.G. GoldstrawR.E. Rami-Porta, D.L. Ball, D.G. Beer, R. Beyruti, V. Bolejack, K.L. Chansky, W.E.E. Eberhardt, J.G. Edwards, F. Galateau-Sallé, F. Gleeson, P.A. Groome, C.W. Kennedy, L.L. Kingsbury, Y. Kim, H. Kondo, M. Krasnik, K. Kubota, A. Lerut, G.A. Lyons, J.P.A.M. Van Meerbeeck, A.K. Mitchell, T. Nakano, Anna Nowak, M.D. Peake, T. Rice, K.E. Rosenzweig, V.W. Rusch, N. Saijo, J.P. Sculier, L. Shemanski, K. Suzuki, Y. Tachimori, C.F. Thomas, W.D. Travis, M.S. Tsao, A.T. Turrisi, J.F. Vansteenkiste, H. Watanabe, Y. Wu, P. Baas, J.J. Erasmus, S. Hasegawa, K. Inai, K.H. Kernstine, H.L.E. Kindler, L.M. Krug, K.L. Nackaerts, H.I. Pass, D.C. Rice, E.H.J.W. Blackstone, S. Call Caja, U. Ahmad, N. Girard, S. Haam, D.R. Gomez, P.E.Y. Van Schil, M. Bae, P. Ströbel, A. Marx, S. Saita, H.A. Wakelee, L. Bertolaccini, E. Vallières, W.J. Scott, S. Su, B. Park, J. Marks, S.L. Khella, R. Shen, M. Rosenberg, V. Tomulescu, C. Foroulis, L. Lang-Lazdunski, A. Billè, J.G. Maessen, M. Keijzers, H.G. Van Veer, C.D. Wright, F. Facciolo, G.L. Palmieri, C. Buonerba, M.K. Ferguson, G. Marulli, P.P. Loehrer, M.S. Kalkat, K.S. Rohrberg, G.K. Daugaard, A. Toker, S. Erus, M. Kimmich, A. Brunelli, M.A. Refai, E. Lim, I. Park, J.Y. Wagner, B.H. Tieu, W. Fang, J. Zhang, Z. Yu, Y. Han, Y. Li, K. Chen, G. Chen, K. Nagai, Y. Fujii, J. Nakajima, N. Ikeda, S. Haraguchi, T. Onuki, I. Yoshino, M. Tsuchida, S. Takahashi, K. Yokoi, M. Hanyuda, H. Niwa, H. Date, Y. Maniwa, S. Miyoshi, A. Iwasaki, T. Okamoto, T. Nagayasu, F. Tanaka, M. Suzuki, K. Yoshida, Y. Okuma, H. Horio, A. Matsumura, M. Higashiyama, H. Suehisa, Y. Sano, K.M. Al Kattan, R.J. Cerfolio, C. Gebitekin, D. Gómez-De Antonio, N.K. Altorki, N.M. Novoa, E.O. Ruffini, M. Scarci, L. Voltolini, W. Weder, W. Zurek, A. Arame, C. Casadio, P. Carbo̧gnani, G.P. Donati, S.H. Keshavjee, W. Klepetko, B. Moser, C.I. Lequaglie, M. Liberman, M. Mancuso, M. Nosotti, L. Spaggiari, P.A.L. Thomas, E.A. Rendina, F. Venuta, M. Anile, J. Schützner, G. Rocco

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Abstract

Copyright © 2014 by the International Association for the Study of Lung Cancer. A universal and consistent stage classification system, which describes the anatomic extent of a cancer, provides a foundation for communication and collaboration. Thymic epithelial malignancies have seen little progress, in part because of the lack of an official system. The International Association for the Study of Lung Cancer and the International Thymic Malignancies Interest Group assembled a large retrospective database, a multispecialty international committee and carried out extensive analysis to develop proposals for the 8th edition of the stage classification manuals. This tumor, node, metastasis (TNM)-based system is applicable to all types of thymic epithelial malignancies. This article summarizes the proposed definitions of the T, N, and M components and describes how these are combined into stage groups. This represents a major step forward for thymic malignancies.
Original languageEnglish
Pages (from-to)S65-S72
JournalJournal of Thoracic Oncology
Volume9
Issue number9
Publication statusPublished - 2014

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