[Truncated abstract] This thesis examines the health outcomes of women exposed to blue asbestos at Wittenoom, Western Australia. Blue asbestos was mined and milled from 1943 to 1966 by the Australian Blue Asbestos Company (ABA) at Wittenoom, 1,600km from Perth in the remote Pilbara region of Western Australia. The original work for this thesis is presented in six manuscripts, some of which have been published in peer-reviewed Journals. The following aims have been investigated. 1. (a) To compare the all-cause mortality rates of women who lived at Wittenoom compared with all-cause mortality rates of the Western Australian female population (b) To assess the exposure-response relationship between asbestos and mortality in women. 2. (a) To compare the incidence rates of common cancers in women who lived at Wittenoom, compared with the incidence rates of these cancers in the Western Australian female population. (b) To assess the exposure-response relationship between asbestos and cancer incidence at various sites in women. 3. (a) To determine if reproductive cancers (ovarian, uterine cervical and corpus and breast) and gestational trophoblastic diseases are associated with asbestos exposure. v (b) To determine if ovarian cancer has been misclassified as malignant peritoneal mesothelioma or vice versa. (c) To determine if colon cancer has been misclassified as malignant peritoneal mesothelioma or vice versa. (d) To assess the exposure-response relationship between asbestos and reproductive cancer incidence. 4. To assess the susceptibility of women to asbestos exposure in comparison with men with similar exposure histories. 5. To predict the future mortality from malignant mesothelioma among women who lived at Wittenoom. '...' The Wittenoom crocidolite industry has had a damaging impact upon the health of the women workers and residents who lived there. Wittenoom women are more likely to die from malignant mesothelioma and lung cancer, all cancers and all causes than women in the Western Australian population. This brief period of crocidolite mining in Western Australia's history will continue to exert a detrimental impact upon the future of the women who lived there, with another 66 to 87 mesotheliomas predicted to occur to the end of 2030.
|Qualification||Doctor of Philosophy|
|Publication status||Unpublished - 2008|