Abstract
This thesis demonstrates that the wide range of diseases caused by Group A Streptococcus (GAS) results in considerable health and economic burdens, both at the population level and throughout the lifetime of the individual. In the short-term, an economic case can be made for population-wide echocardiographic screening for rheumatic heart disease in remote Indigenous communities in the northern regions of Australia. However, a vaccine that reduces all GAS disease by 70% would be cost-effective at a price in line with other modern, publicly funded vaccines, with cellulitis and other skin infections being important targets in addition to throat infections.
Original language | English |
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Qualification | Doctor of Philosophy |
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Award date | 16 Jul 2019 |
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Publication status | Unpublished - 2019 |