Abstract
The determination of the crystal structure of human phosphopantothenoylcysteine synthetase completes our knowledge of the enzyme structures involved in all steps of coenzyme A biosynthesis. This structure provides insight into the differences between bacterial and mammalian forms of the enzyme and may guide the structure-based development of novel antibacterial compounds.
Original language | English |
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Pages (from-to) | 899-900 |
Journal | Structure |
Volume | 11 |
DOIs | |
Publication status | Published - 2003 |