Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 438-441 |
| Journal | Medical Journal of Australia |
| Volume | 189 |
| Issue number | 8 |
| Publication status | Published - 2008 |
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The epidemiology of Helicobacter pylori infection in African refugee children resettled in Australia. / Cherian, S.; Forbes, David; Sanfilippo, Frank; Cook, Angus; Burgner, David.
In: Medical Journal of Australia, Vol. 189, No. 8, 2008, p. 438-441.Research output: Contribution to journal › Article
TY - JOUR
T1 - The epidemiology of Helicobacter pylori infection in African refugee children resettled in Australia
AU - Cherian, S.
AU - Forbes, David
AU - Sanfilippo, Frank
AU - Cook, Angus
AU - Burgner, David
PY - 2008
Y1 - 2008
N2 - Objective: To determine the prevalence and associated epidemiological features of Helicobacter pylon infection in child refugees in Western Australia.Design and participants: Cross-sectional study of 193 eligible African refugee children (aged < 16 years) at their initial health assessment after resettlement in Australia between 1 February and 30 November 2006.Main outcome measures: (i) Prevalence of H. pylori infection determined by monoclonal faecal antigen enzyme immunoassay testing (MFAT); (ii) associations of H. pylori infection with epidemiological factors (age, sex, transit through refugee camps, comorbidities and treatment interventions).Results: MFAT was performed in 182 of the 193 children; 149 of these 182 (82%) had H. pylori infection. Age was an independent predictor of H. pylori infection (odds ratio [OR], 1.18; 95% Cl, 1.07-1.31). No sex differences were observed. Premigration antimalarial therapy (with sulfadoxine-pyrimethamine and artesunate) significantly reduced the prevalence of H. pylori infection (age-adjusted OR, 0.33; 95% Cl, 0.15-0.75).Conclusion: African refugee children have a high prevalence of H. pylori infection. Increasing age is a strong predictor of infection and antimalarial treatment may have a protective effect.
AB - Objective: To determine the prevalence and associated epidemiological features of Helicobacter pylon infection in child refugees in Western Australia.Design and participants: Cross-sectional study of 193 eligible African refugee children (aged < 16 years) at their initial health assessment after resettlement in Australia between 1 February and 30 November 2006.Main outcome measures: (i) Prevalence of H. pylori infection determined by monoclonal faecal antigen enzyme immunoassay testing (MFAT); (ii) associations of H. pylori infection with epidemiological factors (age, sex, transit through refugee camps, comorbidities and treatment interventions).Results: MFAT was performed in 182 of the 193 children; 149 of these 182 (82%) had H. pylori infection. Age was an independent predictor of H. pylori infection (odds ratio [OR], 1.18; 95% Cl, 1.07-1.31). No sex differences were observed. Premigration antimalarial therapy (with sulfadoxine-pyrimethamine and artesunate) significantly reduced the prevalence of H. pylori infection (age-adjusted OR, 0.33; 95% Cl, 0.15-0.75).Conclusion: African refugee children have a high prevalence of H. pylori infection. Increasing age is a strong predictor of infection and antimalarial treatment may have a protective effect.
M3 - Article
VL - 189
SP - 438
EP - 441
JO - Medical Journal Australia
JF - Medical Journal Australia
SN - 0025-729X
IS - 8
ER -