The Effects of the Spine on the Analysis of Peak Wall Stress in Abdominal Aortic Aneurysms

Michael D. Liddelow, Farah Alkhatib, Adam Wittek, Karol Miller

Research output: Chapter in Book/Conference paperConference paperpeer-review


Abdominal aortic aneurysms (AAA) are a chronic degenerative disease, affecting around 7% of men aged 65 years or over. Previous studies on AAA biomechanics either assume the effects of surrounding tissues to be negligible, or do not address the assumption. This study determines the potential for the spine to affect the AAA stress calculations and therefore influence the resulting risk assessment accuracy. Spinal contact boundary conditions on the AAA were manually chosen. Finite element analysis (FEA) was performed on two AAAs adapting the BioPARR workflow to calculate maximum principal stress (MPS) in the isolated AAA and the AAA with spinal contact. The 99th percentile MPS in the spine contact variant was 0.421 MPa, compared to 0.448 MPa in the isolated vessel (0.311 MPa vs. 0.345 MPa, for case 2, respectively). The mean absolute difference of the nodal MPS between variants for case 1 was 0.016 MPa and 0.014 MPa for case 2. Areas of stress on the posterior surface of the AAA in the isolated method appear to be overestimated. However, the overall stress maps of the two variants in both cases indicated almost identical locations of high and low stress. This study indicates that the effect of the spine on AAA biomechanics is mostly negligible, providing the first evidence to justify the common assumption that such impact can be ignore
Original languageEnglish
Title of host publicationComputational Biomechanics for Medicine
Subtitle of host publicationTowards Automation and Robustness of Computations in the Clinic
EditorsMartyn P. Nash, Adam Wittek, Poul M.F. Nielsen, Magdalena Kobielarz, Anju R. Babu, Karol Miller
Place of PublicationSwitzerland
PublisherSpringer Nature Switzerland AG
ISBN (Electronic)9783031349065
ISBN (Print)9783031349058
Publication statusPublished - 12 Aug 2023
Event25th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2022 - Singapore, Singapore
Duration: 18 Sept 202222 Sept 2022


Conference25th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2022

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