The effects of Ephrin-A2 and -A5 on cutaneous development and wound healing

Dulharie Thanuja Wijeratne

The effects of Ephrin-A2 and -A5 on cutaneous development and wound healing

Dulharie Thanuja Wijeratne

Research output: Thesis › Doctoral Thesis

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Abstract

In this thesis the effects of Ephrin-A2 and Ephrin-A5 ligands on cutaneous development and wound healing have been investigated. The research shows the importance of Ephrin-A2 and A5 ligands in hair follicle morphogenesis and cycling; innervation and sensory function of the skin and in wound repair and scar formation. Future work on modulating the interactions of Ephrin-A2 and Ephrin-A5 ligands with the cognate receptors could potentially be a useful therapeutic strategy to improve healing and reduce scarring.

Original language	English
Qualification	Doctor of Philosophy
Publication status	Unpublished - 2014

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title = "The effects of Ephrin-A2 and -A5 on cutaneous development and wound healing",

abstract = "In this thesis the effects of Ephrin-A2 and Ephrin-A5 ligands on cutaneous development and wound healing have been investigated. The research shows the importance of Ephrin-A2 and A5 ligands in hair follicle morphogenesis and cycling; innervation and sensory function of the skin and in wound repair and scar formation. Future work on modulating the interactions of Ephrin-A2 and Ephrin-A5 ligands with the cognate receptors could potentially be a useful therapeutic strategy to improve healing and reduce scarring.",

keywords = "Ephrin, skin, Nerves, wound repair, scar, hair follicle",

author = "Wijeratne, {Dulharie Thanuja}",

year = "2014",

language = "English",

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TY - BOOK

T1 - The effects of Ephrin-A2 and -A5 on cutaneous development and wound healing

AU - Wijeratne, Dulharie Thanuja

PY - 2014

Y1 - 2014

N2 - In this thesis the effects of Ephrin-A2 and Ephrin-A5 ligands on cutaneous development and wound healing have been investigated. The research shows the importance of Ephrin-A2 and A5 ligands in hair follicle morphogenesis and cycling; innervation and sensory function of the skin and in wound repair and scar formation. Future work on modulating the interactions of Ephrin-A2 and Ephrin-A5 ligands with the cognate receptors could potentially be a useful therapeutic strategy to improve healing and reduce scarring.

AB - In this thesis the effects of Ephrin-A2 and Ephrin-A5 ligands on cutaneous development and wound healing have been investigated. The research shows the importance of Ephrin-A2 and A5 ligands in hair follicle morphogenesis and cycling; innervation and sensory function of the skin and in wound repair and scar formation. Future work on modulating the interactions of Ephrin-A2 and Ephrin-A5 ligands with the cognate receptors could potentially be a useful therapeutic strategy to improve healing and reduce scarring.

KW - Ephrin

KW - skin

KW - Nerves

KW - wound repair

KW - scar

KW - hair follicle

M3 - Doctoral Thesis

ER -

The effects of Ephrin-A2 and -A5 on cutaneous development and wound healing

Abstract

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