In this thesis the effects of Ephrin-A2 and Ephrin-A5 ligands on cutaneous development and wound healing have been investigated. The research shows the importance of Ephrin-A2 and A5 ligands in hair follicle morphogenesis and cycling; innervation and sensory function of the skin and in wound repair and scar formation. Future work on modulating the interactions of Ephrin-A2 and Ephrin-A5 ligands with the cognate receptors could potentially be a useful therapeutic strategy to improve healing and reduce scarring.
|Qualification||Doctor of Philosophy|
|Publication status||Unpublished - 2014|