The effects of Ephrin-A2 and -A5 on cutaneous development and wound healing

Dulharie Thanuja Wijeratne

    Research output: ThesisDoctoral Thesis

    93 Downloads (Pure)

    Abstract

    In this thesis the effects of Ephrin-A2 and Ephrin-A5 ligands on cutaneous development and wound healing have been investigated. The research shows the importance of Ephrin-A2 and A5 ligands in hair follicle morphogenesis and cycling; innervation and sensory function of the skin and in wound repair and scar formation. Future work on modulating the interactions of Ephrin-A2 and Ephrin-A5 ligands with the cognate receptors could potentially be a useful therapeutic strategy to improve healing and reduce scarring.
    Original languageEnglish
    QualificationDoctor of Philosophy
    Publication statusUnpublished - 2014

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