The effects of Dexamphetamine and Nabilone on individual perceptual binding windows in healthy volunteers

Mark Lim

Research output: ThesisDoctoral Thesis

52 Downloads (Pure)

Abstract

Forms of hallucinations and delusions in schizophrenia are proposed to occur due to alterations inworking memory, via alterations in perceptual binding. These are thought to occur as a consequence of dopaminergic alterations, but some researchers propose a role for cannabis in the aetiology of the disorder. We tested the hypotheses that dexamphetamine, a dopamine-elevating drug, and nabilone, the psychoactive component of cannabis, would increase the capacity of the perceptual binding mechanism as a factor of working memory. Bi-directional and multimodal effects of dexamphetamine and nabilone were found to depend on the individual, and were not associated with WM alterations.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • The University of Western Australia
Supervisors/Advisors
  • Pixley, Fiona, Supervisor
  • Rodger, Jennifer, Supervisor
  • Martin-Iverson, Mathew, Supervisor
Thesis sponsors
Award date2 Oct 2023
DOIs
Publication statusUnpublished - 2023

Fingerprint

Dive into the research topics of 'The effects of Dexamphetamine and Nabilone on individual perceptual binding windows in healthy volunteers'. Together they form a unique fingerprint.

Cite this